Otoyol 52

O-52
O-52
Adana-Şanlıurfa Motorway; Adana-Şanlıurfa Otoyolu
Route information
	Part of E90 / AH84
Length	365 km (227 mi)
Existed	1992–present
Major junctions
From	O-51 in Yüreğir, Adana; O-53 in Ceyhan, Adana; O-53 in Toprakkale, Osmaniye; O-54 in Şehitkamil, Gaziantep; D.875 in Karaköprü, Şanlıurfa;
To	D.400 in Haliliye, Şanlıurfa
Location
Country	Turkey
Regions	Mediterranean, Southeastern Anatolia
Provinces	Adana, Osmaniye, Gaziantep, Kahramanmaraş, Şanlıurfa
Major cities	Adana, Ceyhan, Osmaniye, Gaziantep, Nizip, Şanlıurfa
Highway system
	Highways in Turkey; Motorways List; ; State Highways List; ;

Otoyol 52 (English: Motorway 52), abbreviated as O-52, a.k.a. Adana-Şanlıurfa Otoyolu (English: Adana-Şanlıurfa Motorway), is a toll motorway in the regions of Mediterranean and Southeastern Anatolia in Turkey, connecting the cities Adana and Şanlıurfa. The motorway is part of European route E90 and Asian Highway 84. The O-52 starts from the eastern terminus of The O-51, runs eastward through Osmaniye, Gaziantep and terminates east of Şanlıurfa. The O-52 is currently the second longest Motorway in Turkey being only 5 km shorter than the O-4.

The highway sustained damage in the 2023 Turkey–Syria earthquake.^[1]

Exit list

Province	District	km	mi	Exit	Destination	Notes
Adana	Yüreğir	0.0	0.0	K1	Dr. Mithat Özsan Blv.	Continues as O-51 to Mersin
	Sarıçam			K2	D.815 — Pınarbaşı
	Sarıçam			K3	İnönü Blv.
	Ceyhan			K4	D.400 — Osmaniye
				Yılankale Toll Plaza
				K5	D.817 — Ceyhan
				K6	O-53 — İskenderun	Westbound entrance and eastbound exit
Osmaniye	Toprakkale			K7	O-53 — İskenderun	Westbound exit and eastbound entrance
	Toprakkale			K8	P.80-75 — Osmaniye
	Osmaniye			K9	P.80-50 — Toprakkale
	Düziçi			K10	P.80-01 — Düziçi
	Bahçe			Taşoluk Tunnel
				K11	D.400 — Bahçe
				Ayran Tunnel
				Kızlaç Tunnel
Gaziantep	Nurdağı			Aslanlı Tunnel
Gaziantep	Nurdağı			K12	D.825 — Nurdağı
Kahramanmaraş	Narlı			K13	D.835 — Narlı
Gaziantep	Şehitkamil			K14	D.835 — Gaziantep
				K15	D.835 — Gaziantep
				K16	O-54 (Gaziantep Bltwy) — D.400 West
	Nizip			K17	Nizip connector — Nizip
Euphrates				Euphrates Viaduct
Şanlıurfa	Birecik			K18	Birecik connector — Birecik
	Suruç			K19	Suruç connector — Onbirnisan
	Şanlıurfa			Şanlıurfa West Toll Plaza
				K20	Şanlıurfa West connector — Koçören
				K21	D.885 — Şanlıurfa
				K22	D.400 — Hakkari