Lowe is a surname. Notable persons with that name include:
- Aaron Lowe (born 1974), Canadian ice dancer
- Adolph Lowe (1893–1995), German sociologist and economist
- Al Lowe (born 1946), American computer game programmer
- Alan Lowe (born 1961), Canadian politician
- Alex Lowe (1958–1999), American mountaineer
- Alex Lowe (born 1968), English actor
- Alf Lowe, GC (born 1931), British sailor
- Alice Lowe (born 1977), English actress
- Andrea Lowe (born 1975), English actress
- Andrew Lowe (born 1959), Canadian scientist
- Ann Lowe (1898–1981), American fashion designer
- Annie Lowe (1834–1910), Australian suffragist
- Arthur Lowe (1915–1982), English actor
- Arvie Lowe Jr. (born 1978), American actor
- Ben Lowe (born 1985), Australian rugby League player
- Bernie Lowe (1917–1993), American music producer
- Bert Lowe (1912–1933), New Zealand boxer
- Bobby Lowe (1865–1951), American baseball player
- Brandon Lowe (born 1994), American baseball player
- Bull Lowe (1895–1939), American football player
- Caitlin Lowe (born 1985), American softball player
- Cass Lowe, British musician
- Catherine Lowe (born 1986), American graphic designer and reality television star
- Chad Lowe (born 1968), American actor
- Charles Lowe (1890–1953), English cricketer
- Charles P. Lowe, pioneer recording artist
- Charles Herbert Lowe (1920–2002), American biologist and herpetologist
- Chris Lowe (born 1949), British journalist
- Chris C. Lowe (born 1987), American basketball player
- Chris S. Lowe (born 1959), British musician with the Pet Shop Boys
- Craig Lowe (1957–2023), American mayor of Gainesville, FL
- Crystal Lowe (born 1981), Canadian actress
- Cyril Lowe (1891–1983), British rugby player and flying ace
- Daisy Lowe (born 1989), English fashion model
- Daniel Lowe (born 1992), American sports shooter
- Darren Lowe (born 1960), Canadian ice hockey player
- Darren Lowe, American lacrosse player
- David Lowe (disambiguation)
- Derek Lowe (born 1973), American baseball player
- Doug Lowe (born 1942), Australian politician
- Douglas Lowe (disambiguation)
- Earl Lowe (born c. 1950), Jamaican musician
- Ed Lowe (businessman) (1920–1995), American inventor
- Ed Lowe (1946–2011), American journalist
- Eddie Lowe (1925–2009), English footballer
- Eddie Lowe (born 1960), American politician and player of Canadian football
- Edmund Lowe (1890–1971), American actor
- Edward Lowe (c. 1690 – c. 1724), English pirate
- Edward Clarke Lowe (1823–1912), English educator
- Edward Joseph Lowe (1825–1900), English botanist
- Edward T. Lowe Jr. (1880–1973), American film producer
- E.J. Lowe (1950–2014), English philosopher
- Emilio Lowe, a fictional archer in the anime Black Cat
- Emily Lowe (?–1882), British travel writer
- Enoch Louis Lowe (1820–1892), American politician
- Ernest Anthony Lowe (1928–2014), British economist
- Ethan Lowe (born 1991), Australian rugby league player
- Florence Leontine Lowe (1901–1975), American aviator
- Sir Francis Lowe, 1st Baronet (1852–1929), British politician
- Frank Lowe (1943–2003), American musician
- Frank Lowe (born 1941), British businessman
- Fred Lowe (born 1947), American weightlifter
- Gary Lowe (1934–2017), American football player
- Gavin Lowe, American computer scientist
- George Lowe (disambiguation)
- Georgina Lowe, British television producer
- Gerry Lowe (1927–2018), English rugby union and rugby league footballer
- Sir Gordon Lowe (1884–1972), British tennis player
- Greg Lowe, American mountain climber
- Gregg Lowe (born 1986), British actor
- Graham Lowe (born 1946), New Zealand rugby league football coach
- H. F. Lowe, English cricketer
- Hannah Lowe (born 1976), British writer
- Harold Lowe (1882–1944), fifth officer on the RMS Titanic
- Harry Lowe (1886–1958), English footballer
- Harry James Lowe, Jr. (1922–1942), American sailor
- Sir Hudson Lowe (1769–1844), Anglo-Irish military officer and Governor of St Helena
- Ian Lowe (born 1942), Australian scientist
- Jack Lowe, Sr. (1913–1980), American businessman
- Jack Lowe, Jr. (born 1939), American businessman
- Jaiman Lowe (born 1980), Australian rugby player
- Jamal Lowe (born 1994), Jamaican footballer
- James Lowe (disambiguation)
- Janet Lowe (1940–2019), American writer
- Jason Lowe (disambiguation)
- Jean Lowe (born 1960), American artist
- Jeff Lowe (1950–2018), American alpinist
- Jemma Lowe (born 1990), British swimmer
- Jesse Lowe (1814–1868), American politician
- Jet Lowe (born 1946), American photographer
- Jez Lowe (born 1955), British musician
- Jim Lowe (1923–2016), American musician
- Bl. John Lowe (1553–1586), English priest and martyr
- John Lowe (1899–1960), Canadian priest
- John Lowe (1912–1995), British footballer
- John Lowe (born 1945), British darts player
- John Charles Lowe (born 1942), British musician
- Jonathan Lowe (1950–2014), British philosopher
- Joseph Lowe (1845–1899), American saloon keeper
- Josh Lowe (born 1998), American baseball player
- Karl Lowe (born 1984), New Zealand rugby union player
- Kate Lowe (born 1975), English cricketer
- Keegan Lowe (born 1993), American Canadian hockey player
- Keith Lowe (born 1985), English footballer
- Kendra Lowe (born 1962), English netball player
- Kenneth Gordon Lowe (1917–2010), Scottish physician
- Kenny Lowe (born 1961), English footballer
- Kevin Lowe (born 1959), Canadian hockey player
- Lisa Lowe, American academic
- Mark Lowe (born 1983), American baseball player
- Martha Perry Lowe (1829–1902), American poet, activist
- Mary Johnson Lowe (1924–1999), American judge
- Max Lowe (born 1997), English footballer
- Megan Lowe (1915–2017), English cricketer
- Ming C. Lowe (born 1945), American artist
- Mundell Lowe (1922–2017), American jazz guitarist
- Muriel Lowe (1914–1966), English cricketer
- Nate Lowe (born 1995), American baseball player
- Neil Lowe (born 1978), English rugby player
- Nick A. Lowe (born 1979), American comic book editor
- Nick D. Lowe (born 1949), British singer
- Omare Lowe (born 1978), American football player
- Onandi Lowe (born 1974), Jamaican soccer player
- Paddy Lowe (born 1962), British racing engineer
- Paul Lowe (born 1936), American football player
- Pearl Lowe (born 1970), British musician
- Percy Lowe (1870–1948), English surgeon and ornithologist
- Peter Lowe (disambiguation)
- Phil Lowe (born 1950), English rugby league footballer
- Philip Lowe (born 1961), Australian economist
- Rachel Lowe (born 1977), British entrepreneur
- Rachel Lowe (born 2000), Australian soccer player
- Ralph P. Lowe (1805–1883), American politician
- Rebecca Lowe (born 1980), British journalist
- Richard Barrett Lowe (1902–1972), Governor of American Samoa and Guam
- Richard Thomas Lowe (1802–1874) British naturalist
- Rob Lowe (born 1964), American actor
- Robert Lowe, American singer
- Robert Lowe, 1st Viscount Sherbrooke (1811–1892), British statesman
- Robson Lowe (1905–1997), British philatelist
- Rosemary Lowe (1921–2014), English ichthyologist, ecologist, and limnologist
- Rosie Lowe (born 1989), English musician
- Ross Lowe (1928–1955), Canadian hockey player
- Rupert Lowe (born 1957), British businessman
- Ruth Lowe (1914–1981), Canadian musician
- Ryan Lowe (born 1978), English footballer
- Sam Lowe (1867–1947), English cricketer
- Sammy Lowe (1918–1993), American musician
- Sean Lowe (disambiguation)
- Sid Lowe (born 1976), British journalist
- Sidney Lowe (born 1960), American basketball coach
- Simon Lowe (born 1973), British actor
- Sophie Lowe (born 1990), English-born Australian actress
- Stephen Lowe (disambiguation)
- Steven Lowe, British writer
- Susan Lowe (born 1948), American actress
- Ted Lowe (1920–2011), British snooker commentator
- Thaddeus S. C. Lowe (1832–1913), American aeronaut, scientist and inventor
- Thomas Lowe (Lord Mayor) (d. 1623), English politician
- Thomas Lowe (politician) (1812–1875), American politician
- Thomas Lowe (tenor) (c.1719–1783), English singer
- Tiffany Anastasia Lowe (born 1972), daughter of musician Carlene Carter
- Titus Lowe (1877–1959), English-American clergyman
- Todd Lowe (born 1977), American actor
- Tom Lowe, American writer
- Tom E. Lowe (born 1975), British disc jockey
- Tom P. Lowe (born 1973), British singer
- Trent Lowe (born 1984), Australian cyclist
- Vaughan Lowe (born 1952), British lawyer
- W. H. M. Lowe (1861–1944), British army officer
- William C. Lowe (1941–2013), American engineer and businessman
- William M. Lowe (1842–1882), American politician
- William W. Lowe (1873–1945), English cricketer
- Woodrow Lowe (born 1954), American football player
- Zane Lowe (born 1973), New Zealand disc jockey