ZFAND5

Zinc finger AN1-type containing 5 is a protein that in humans is encoded by the ZFAND5 gene.

ZFAND5
Identifiers
Aliases	ZFAND5, ZA20D2, ZFAND5A, ZNF216, zinc finger AN1-type containing 5
External IDs	OMIM: 604761; MGI: 1278334; HomoloGene: 21215; GeneCards: ZFAND5; OMA:ZFAND5 - orthologs
Gene location (Human) Chr. Chromosome 9 (human) Band 9q21.13 Start 72,351,413 bp End 72,365,235 bp
Gene location (Mouse) Chr. Chromosome 19 (mouse) Band 19 B|19 14.32 cM Start 21,249,642 bp End 21,264,204 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in mucosa of paranasal sinus gastric mucosa seminal vesicula Skeletal muscle tissue of rectus abdominis right lung oocyte tibial nerve tibia biceps brachii Skeletal muscle tissue of biceps brachii Top expressed in habenula extensor digitorum longus muscle triceps brachii muscle medial head of gastrocnemius muscle muscle of thigh plantaris muscle vastus lateralis muscle sternocleidomastoid muscle thoracic diaphragm digastric muscle More reference expression data BioGPS n/a
Gene ontology Molecular function DNA binding zinc ion binding protein binding metal ion binding molecular function Cellular component cytoplasm cellular component Biological process fibroblast migration skeletal system morphogenesis platelet-derived growth factor receptor signaling pathway face development respiratory system process vasculature development in utero embryonic development smooth muscle tissue development biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 7763 22682 Ensembl ENSG00000107372 ENSMUSG00000024750 UniProt O76080 O88878 RefSeq (mRNA) NM_006007 NM_001102420 NM_001102421 NM_001278243 NM_001278244 NM_001278245 NM_009551 RefSeq (protein) NP_001095890 NP_001095891 NP_001265172 NP_001265173 NP_001265174 NP_005998 NP_033577 Location (UCSC) Chr 9: 72.35 – 72.37 Mb Chr 19: 21.25 – 21.26 Mb PubMed search
Wikidata
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Further reading

• Huang J, Teng L, Li L, Liu T, Li L, Chen D, Xu LG, Zhai Z, Shu HB (April 2004). "ZNF216 Is an A20-like and IkappaB kinase gamma-interacting inhibitor of NFkappaB activation". J. Biol. Chem. 279 (16): 16847–53. doi:10.1074/jbc.M309491200. PMID 14754897.
• Hishiya A, Ikeda K, Watanabe K (2005). "A RANKL-inducible gene Znf216 in osteoclast differentiation". J. Recept. Signal Transduct. Res. 25 (3): 199–216. doi:10.1080/10799890500240781. PMID 16194934. S2CID 11227257.
• Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD (November 2009). "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip". Am. J. Hum. Genet. 85 (5): 628–42. doi:10.1016/j.ajhg.2009.10.014. PMC 2775832. PMID 19913121.
• Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S (October 2010). "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study". Diabetes Care. 33 (10): 2250–3. doi:10.2337/dc10-0452. PMC 2945168. PMID 20628086.
• He G, Sun D, Ou Z, Ding A (July 2012). "The protein Zfand5 binds and stabilizes mRNAs with AU-rich elements in their 3'-untranslated regions". J. Biol. Chem. 287 (30): 24967–77. doi:10.1074/jbc.M112.362020. PMC 3408148. PMID 22665488.