WAY-261240 is a drug which acts as a potent and selective 5-HT2C receptor agonist, though its affinity at other serotonin receptors has not been disclosed. It produces anorectic effects in animal studies. A large family of related derivatives are known.[1][2][3][4][5][6]
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Formula | C16H15Cl2NO |
Molar mass | 308.20 g·mol−1 |
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See also
editReferences
edit- ^ Lee J, Jung ME, Lee J (November 2010). "5-HT2C receptor modulators: a patent survey". Expert Opinion on Therapeutic Patents. 20 (11): 1429–55. doi:10.1517/13543776.2010.518956. PMID 20849206. S2CID 32729624.
- ^ WO 2006116165, Heffernan GD, Stack GP, Gross JL, Zhou D, Gao H, "Chromane and chromene derivatives and uses thereof", published 2 November 2006, assigned to Wyeth.
- ^ WO 2005044812, Gross JL, Williams MJ, Stack GP, Gao H, Zhou D, "Dihydrobenzofuranyl alkanamine derivatives as 5ht2c agonists", published 19 May 2005, assigned to Wyeth.
- ^ WO 2006116158, Zhou D, Stack GP, Gross JL, Gao H, "Benzodioxane and benzodioxolane derivatives and uses thereof", published 2 November 2006, assigned to Wyeth.
- ^ WO 2008052075, Stack GP, Hatzenbuhler NT, Zhou D, "Benzoxazine derivatives and uses thereof", published 2 May 2008, assigned to Wyeth.
- ^ WO 2008052078, Stack GP, Luoni G, Bianchi I, Vallese S, "Benzoxathiine and benzoxathiole derivatives and uses thereof", published 2 May 2008, assigned to Wyeth.