user:Lacarubb/RNA binding protein
Wikipedia Project Proposal: RNA-binding proteins
Brianna Lacarubba Eun Young (Anna) Han So hee Kim
Current information on Wikipedia page: Only general definition of RNA-binding protein is present without much detail on its functions, structure and types.
Outline
1) General overview of RNA-binding protein 2) History of RNA-binding protein 3) General structure and an interaction with RNA -Modular design of RNA-binding proteins 4) RNA-binding activity and recognition (specificity) of RNA sequences 5) Diversity of RNA-binding proteins -mRNA binding proteins -snRNA binding proteins -micro-RNA binding proteins
- Specific examples will be included
6) Post-transcriptional control - Biogenesis - Stability - Function - Transport - Cellular localization
- Specific examples will be included
7) RNA-binding proteins’ function during germ line and embryonic development 8) Recent findings -Role of RNA-binding protein Sam68 on dendrites -Effects of RNA-binding protein Slr1 on Candida albicans filamentation and virulence -An RNA-binding protein associated with Src in mitosis
Sources:
http://www.ncbi.nlm.nih.gov/pubmed/18342629
http://www.wormbook.org/chapters/www_RNAbindingproteins/RNAbindingproteins.html
http://www.ncbi.nlm.nih.gov/pubmed/23382180
http://www.nature.com/nature/journal/v368/n6474/abs/368867a0.html
http://www.ncbi.nlm.nih.gov/pubmed/23381995
http://www.nature.com/nrm/journal/v3/n3/full/nrm760.html
http://www.nature.com/nrm/journal/v8/n3/full/nrm2124.html#top
http://www.nature.com/nrm/journal/v8/n6/full/nrm2178.html
http://rbpdb.ccbr.utoronto.ca/
Work-load distribution:
So hee Kim: Section 1,2,3,4 Brianna Lacarubba: Section 5,6 Eun Young (Anna) Han: Section 7,8
- Subject to change