User:GAThrawn22/Sandbox/protboxtest2

Insulin
Insulin hexamers
Gene code:	HUGO code:INS
Gene type:	Protein coding
Molecular Weight:	11982 (Da)
Structure:	Solution Structure of Human pro-Insulin Polypeptide
Protein type:	insulin family
Functions:	glucose regulation
Domains:	INS
Motifs:	SP
Diseases:	familial hyperproinsulinemia
Pharmaceuticals:	Humulin, Humalog (Eli Lilly) and Novolin(Novo Nordisk)
Taxa expressing:	Homo sapiens; homologs: many metazoan taxa
Cell types:	pancreas
Subcellular localization:	extracellular
Covalent modifications:	glycation, proteolytic cleavage
Other names:	proinsulin

2-oxoglutarate dehydrogenase E1 component (α-Ketoglutarate dehydrogenase) [[Image:|300px]] Gene code: HUGO code:OGDH Gene type: protein coding Molecular Weight: 115942 (Da) Protein type: Enzyme: Dehyrogenase Functions: converts alpha ketoglutarate to succinyl CoA Catalytic activity: 2-oxoglutarate + [dihydrolipoyllysine-residue succinyltransferase] lipoyllysine = [dihydrolipoyllysine-residue succinyltransferase] S-succinyldihydrolipoyllysine + CO(2) Cofactor(s): Thiamine pyrophosphate Enzyme Regulation: Catabolite repressed Diseases: Alpha-Ketoglutarate Dehydrogenase Deficiency Taxa expressing: Homo sapiens; homologs: ubiquitous among oxidatively respiring organisms Cell types: ubiquitous among aerobic cells Subcellular localization: mitochondrion Other names: Alpha-ketoglutarate dehydrogenase Pathway(s): Citric acid cycle, Lysine degradation Symbol(s): CF Entrez: 1431 OMIM: 118950 RefSeq: NM_004077 UniProt: O75390 EC number: 4.1.3.7 Locus: Chr. 12 p11-qter