Thiothinone

Thiothinone
Clinical data
Other names	β-Ketomethiopropamine; βk-Methiopropamine; βk-MPA
Legal status
Legal status	DE: NpSG (Industrial and scientific use only); UK: Class B;
Identifiers
	IUPAC name 2-(methylamino)-1-(thiophen-2-yl)propan-1-one;
CAS Number	24065-17-6 ; 54817-67-3 (hydrochloride);
PubChem CID	12198617;
ChemSpider	16113492;
UNII	8C758Z7L72;
CompTox Dashboard (EPA)	DTXSID901031598 ;
Chemical and physical data
Formula	C8H11NOS
Molar mass	169.24 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(C(=O)C1=CC=CS1)NC;
	InChI InChI=1S/C8H11NOS/c1-6(9-2)8(10)7-4-3-5-11-7/h3-6,9H,1-2H3; Key:DOZQPYDMJMLVKX-UHFFFAOYSA-N;

Thiothinone, also known as β-ketomethiopropamine or βk-methiopropamine (βk-MPA) is a stimulant that is the β-keto-substituted analog of methiopropamine and has been sold online as a designer drug.^[1]^[2]^[3] It is structurally related to methcathinone however the phenyl group has been substituted for thiophene instead.

Thiothinone was also reported to be a pyrolysis product of methiopropamine.^[4]

References

^ "2-Thiothinone (hydrochloride)". Cayman Chemical. Retrieved 9 September 2015.
^ Blicke FF, Burckhalter JS (March 1942). "α-Thienylaminoalkanes". Journal of the American Chemical Society. 64 (3): 477–480. doi:10.1021/ja01255a001.
^ Gambaro V, Casagni E, Dell'Acqua L, Roda G, Tamborini L, Visconti GL, Demartin F (January 2016). "Identification and characterization of a new designer drug thiothinone in seized products". Forensic Toxicology. 34 (1): 174–178. doi:10.1007/s11419-015-0289-2. S2CID 25991798.
^ Bouso ED, Gardner EA, O'Brien JE, Talbot B, Kavanagh PV (July–August 2014). "Characterization of the pyrolysis products of methiopropamine". Drug Testing and Analysis. 6 (7–8): 676–83. doi:10.1002/dta.1571. PMID 24166818.

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[1] "2-Thiothinone (hydrochloride)". Cayman Chemical. Retrieved 9 September 2015.

[2] Blicke FF, Burckhalter JS (March 1942). "α-Thienylaminoalkanes". Journal of the American Chemical Society. 64 (3): 477–480. doi:10.1021/ja01255a001.

[3] Gambaro V, Casagni E, Dell'Acqua L, Roda G, Tamborini L, Visconti GL, Demartin F (January 2016). "Identification and characterization of a new designer drug thiothinone in seized products". Forensic Toxicology. 34 (1): 174–178. doi:10.1007/s11419-015-0289-2. S2CID 25991798.

[4] Bouso ED, Gardner EA, O'Brien JE, Talbot B, Kavanagh PV (July–August 2014). "Characterization of the pyrolysis products of methiopropamine". Drug Testing and Analysis. 6 (7–8): 676–83. doi:10.1002/dta.1571. PMID 24166818.

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[4]

Thiothinone

See also

References