Talk:Staphylococcus saprophyticus

add nitrite positive or negative on UDip

add nitrite positive or positive on UDip [Urine Dip]

Thanks! 68.61.150.75 (talk) 22:01, 27 November 2010 (UTC)

gram positive or gram negative and shape? —Preceding unsigned comment added by 207.38.139.148 (talk) 04:28, 4 February 2011 (UTC)

Is this a question about the organism in general? In that case, it's Gram-Positive Cocci. You can find this by clicking the Staphylococcus link. I'd think that if you were this deep into it (looking at the species level), and were aware of gram staining, you should know that staph is gram-positive cocci. Then again, I don't see how adding those few words would make a big difference. I guess I'm neutral on the subject of whether it should be here. --Major_Small (talk) 16:53, 4 March 2012 (UTC)

Confusing bit in first Paragraph

S. Saprophyticus subsp. saprophyticus is distinguished by its being nitrate negative and pyrrolidonyl arylamidase negative while S. :Saprophyticus subsp. bovis is nitrate negative and pyrolidonyl arymamidase negative

Other than the extra 'r' in "pyrolidonlyl", and the (what I assume is a) mis-spelling of "arylamidase", is there supposed to be a difference here?

Clearly from somebody inexperienced in the field. --Major_Small (talk) 16:36, 4 March 2012 (UTC)

Comment

Comment/Concern: Any instruction to drink diluted bicarb (baking) should clearly state that excess bicarb can disrupt acid-base balance.

Lifesnadir (talk) 18:06, 15 August 2014 (UTC)

Treatment section is utter bollocks.

   S. saprophyticus urinary tract infections are usually treated with trimethoprim-sulfamethoxazole or with a quinolone such as norfloxacin.[3]

This is true.

    Since S. Saprophyticus has begun developing a resistance to antibiotics, and because urinary tract infections often recur after a course of antibiotics is taken, natural treatments for urinary tract infections caused by S. Saprophyticus also must be considered. 

Unsupported statement, biased towards unproven treatment.

    S. Saprophyticus forms an aggressive biofilm which may protect it from being washed out the bladder and from the ordinary defenses of the immune system. 

Unsupported statement -- this has to do with medical devices, not with bladder infections.

         Drinking water with baking soda in appropriate doses may disrupt the biofilms of S. Saprophyticus and inhibit the growth of their bacterial colonies.[8]

Article describes biofilm formation on MEDICAL EQUIPMENT and SURFACES. Does not apply to people.

         Cranberry tablets or juice have been shown to inhibit the growth of new biofilms, but have not been shown to disrupt older established biofilms.[9][10] 

[9] is about biofilm formation on MEDICAL EQUIPMENT. [10] is an unrelated article about Vitamin C.

       Perhaps a potential way to disrupt staph saprophyticus biofilms is to 'expand' the bladder by drinking a large volume of water, then forcibly contract it. 

Unsupported supposition.

      Curcumin or turmeric supplements may have an antibacterial effect against S. Saprophyticus as they induce the body to produce cAMP.[11] 

I quote directly from the article (which, I may add, is generally about neuroscience, not infections): "Curcumin is known to exert direct antibacterial activity against a wide spectrum of bacteria [83-88]. In the absence of light, curcumin exhibited negligible effect against bacteria." Italics added.

Also, the article mentions cAMP (cyclic adenosine monophosphate) only in one instance, and it has nothing to do with anything about killing bacteria, or inducing the body to produce cAMP: "The kinase enzymes that are implicated in hyperphosphorylation include glycogen synthase kinase 3β (GSK-3β), cyclin-dependent protein kinase 5 (CDK5), cAMP-dependent protein kinase (PKA), mitogen-activated protein kinase (MAPK), calcium-calmodulin-dependent kinase-II (CAMK II) and microtubule affinity-regulating kinase (MARK) [182-186]. Among them, GSK-3β and MARK have received significant attention as potential therapeutic targets for AD treatment using kinase inhibitory drugs". Nothing to do with bacteria, or with inducing the body to produce cAMP.

   cAMP may kill bacteria by creating pores in bacterial cell membranes.[12] 

The article referenced is talking about something entirely different than the previous article, conflating two entirely different things: rather than cAMP -- cyclic adenosine monohposphate, the article is referring to CAMPS, "cationic antimicrobial peptides (CAMPs)".

      Other ways to combat these infections without antibiotics may include eating raw garlic and cinnamon, as demonstrated in a science fair project.[13]

While I adore the inclusion of an in vitro study done for a science fair, it is a far cry from proof of in vivo effect.

I am editing the section to remove the questionable statements.

Cranberry juice

This sentence is untrue-- "The many home remedies or natural treatments for urinary tract infections are not clinically proven, such as cranberry juice, alkalinization, and many types of common herbs and spices."

Cranberry juice has recently been proven to prevent UTIs. Here are two sources as evidence:

https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD001321.pub6/full

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8412316/ 138.87.148.94 (talk) 19:42, 24 April 2024 (UTC)