Talk:3C-like protease
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Update - new data on SARS-CoV-2 main protease function
editTheres new data published on cleavage of cellular proteins as well as viral proteins by SARS-CoV-2 main protease - including PNN, PAICS and GOLGA3. The reference is [1]. I would add this, but I am an author on the paper so have a conflict of interest. --Edemmott (talk) 15:16, 24 September 2021 (UTC)
References
- ^ Meyer, Bjoern; Chiaravalli, Jeanne; Gellenoncourt, Stacy; Brownridge, Philip; Bryne, Dominic P.; Daly, Leonard A.; Grauslys, Arturas; Walter, Marius; Agou, Fabrice; Chakrabarti, Lisa A.; Craik, Charles S.; Eyers, Claire E.; Eyers, Patrick A.; Gambin, Yann; Jones, Andrew R.; Sierecki, Emma; Verdin, Eric; Vignuzzi, Marco; Emmott, Edward (December 2021). "Characterising proteolysis during SARS-CoV-2 infection identifies viral cleavage sites and cellular targets with therapeutic potential". Nature Communications. 12 (1): 5553. doi:10.1038/s41467-021-25796-w.
Graphic
editThe article’s current primary graphic is not a normal wild-type representation of a coronavirus’ nor SARS-CoV’s main protease. The main protease is not an oktamer. The image shown was the result of a single laboratory experiment in 2009. This graphic should be changed. Ricksher (talk) 08:36, 13 July 2020 (UTC)
- Good point. The graphic was changed to a dimer. --Guest2625 (talk) 11:33, 13 July 2020 (UTC)
A Commons file used on this page or its Wikidata item has been nominated for deletion
editThe following Wikimedia Commons file used on this page or its Wikidata item has been nominated for deletion:
Participate in the deletion discussion at the nomination page. —Community Tech bot (talk) 14:38, 15 July 2021 (UTC)
Copyright problem removed
edit
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