Bedřich Smetana (1824–1884) was a Czech composer.
Smetana may also refer to:
- Smetana (crater), a crater on Mercury
- Smetana (dairy product), an East European version of sour cream
- Smetana, Texas, US
- Smetana, a village and part of Plchovice in the Czech Republic
- Ondřej Smetana (footballer) (born 1982), Czech footballer
- Ondřej Smetana (racing driver), Czech racing driver
- Zdenek Smetana (1925–2016), Czech animator and director