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SPIKE (Signaling Pathways Integrated Knowledge Engine) is a database of highly curated interactions for particular human pathways.[1]
 | |
| Content | |
|---|---|
| Description | highly curated human signaling pathways. |
| Organisms | Homo sapiens |
| Contact | |
| Research center | Sackler School of Medicine, Tel Aviv University, Israel. |
| Laboratory | Department of Human Molecular Genetics and Biochemistry, |
| Authors | Arnon Paz |
| Primary citation | Paz & al. (2011)[1] |
| Release date | 2010 |
| Access | |
| Website | http://www.cs.tau.ac.il/~spike/ |
| Download URL | http://www.cs.tau.ac.il/~spike/formats.html |
Development
editSPIKE was developed by Ron Shamir's computational biology group in cooperation with the group of Yosef Shiloh, an Israel Prize recipient for his research in systems biology, and the group of Karen Avraham, a leading researcher of human deafness, all from Tel Aviv University.
See also
editReferences
edit- ^ a b Paz, Arnon; Brownstein Zippora; Ber Yaara; Bialik Shani; David Eyal; Sagir Dorit; Ulitsky Igor; Elkon Ran; Kimchi Adi; Avraham Karen B; Shiloh Yosef; Shamir Ron (Jan 2011). "SPIKE: a database of highly curated human signaling pathways". Nucleic Acids Res. 39 (Database issue). England: D793-9. doi:10.1093/nar/gkq1167. PMC 3014840. PMID 21097778.
External links
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