A preemptive strike refers to a surprise attack launched with the stated intention of countering an anticipated enemy offensive.
Preemptive strike may also refer to:
- Preemptive Strike (album), a retrospective compilation album of DJ Shadow's singles released on the UK record label Mo'Wax
- Pre-Emptive Strike, a three-track release by American heavy metal band Five Finger Death Punch
- "Preemptive Strike" (TNG episode), a seventh season episode of Star Trek: The Next Generation
- Pre-emptive nuclear strike