Oxaceprol

Oxaceprol
Clinical data
Other names	(2S,4R)-1-acetyl-4-hydroxypyrrolidine-2-carboxylic acid
AHFS/Drugs.com	International Drug Names
ATC code	D11AX09 (WHO) M01AX24 (WHO);
Identifiers
	IUPAC name (4R)-1-acetyl-4-hydroxy-L-proline;
CAS Number	33996-33-7 ;
PubChem CID	65784;
ChemSpider	59203;
UNII	Q0XV76B96L;
KEGG	D07215 ;
ChEMBL	ChEMBL1407356;
CompTox Dashboard (EPA)	DTXSID2046410 ;
ECHA InfoCard	100.047.058
Chemical and physical data
Formula	C7H11NO4
Molar mass	173.168 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(=O)N1C[C@@H](C[C@H]1C(=O)O)O;
	InChI InChI=1S/C7H11NO4/c1-4(9)8-3-5(10)2-6(8)7(11)12/h5-6,10H,2-3H2,1H3,(H,11,12)/t5-,6+/m1/s1; Key:BAPRUDZDYCKSOQ-RITPCOANSA-N;
	(verify)

Oxaceprol is an anti-inflammatory drug used in the treatment of osteoarthritis.^[1] It is derived from L-proline, a DNA-encoded amino acid. The active effect of Oxaceprol is to inhibit the adhesion and migration of white blood cells.^[2]

References

^ Herrmann G, Steeger D, Klasser M, Wirbitzky J, Fürst M, Venbrocks R, et al. (2000). "Oxaceprol is a well-tolerated therapy for osteoarthritis with efficacy equivalent to diclofenac". Clinical Rheumatology. 19 (2): 99–104. doi:10.1007/s100670050025. PMID 10791619. S2CID 25654850.
^ Clayton JJ (August 2007). "Nutraceuticals in the management of osteoarthritis". Orthopedics. 30 (8): 624–9, quiz 630-1. doi:10.3928/01477447-20070801-13. PMID 17727018. Retrieved 2013-06-08.

External links

"Oxaceprol". Drug Information Portal. U.S. National Library of Medicine.

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[pmid10791619-1] Herrmann G, Steeger D, Klasser M, Wirbitzky J, Fürst M, Venbrocks R, et al. (2000). "Oxaceprol is a well-tolerated therapy for osteoarthritis with efficacy equivalent to diclofenac". Clinical Rheumatology. 19 (2): 99–104. doi:10.1007/s100670050025. PMID 10791619. S2CID 25654850.

[Clayton2007-2] Clayton JJ (August 2007). "Nutraceuticals in the management of osteoarthritis". Orthopedics. 30 (8): 624–9, quiz 630-1. doi:10.3928/01477447-20070801-13. PMID 17727018. Retrieved 2013-06-08.

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