Ornithine oxoglutarate

Ornithine oxoglutarate
	Ornithine (top) and ketoglutaric acid (bottom)
Clinical data
ATC code	A05BA06 (WHO) ;
Identifiers
	IUPAC name 2-Oxopentanedioic acid - L-ornithine (1:1);
CAS Number	34414-83-0 ;
PubChem CID	78866;
ChemSpider	71201;
CompTox Dashboard (EPA)	DTXSID30958449 DTXSID20187988, DTXSID30958449 ;
ECHA InfoCard	100.047.261 100.023.615, 100.047.261
Chemical and physical data
Formula	C10H18N2O7
Molar mass	278.261 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C(C[C@@H](C(=O)O)N)CN.C(CC(=O)O)C(=O)C(=O)O;
	InChI InChI=1S/C5H12N2O2.C5H6O5/c6-3-1-2-4(7)5(8)9;6-3(5(9)10)1-2-4(7)8/h4H,1-3,6-7H2,(H,8,9);1-2H2,(H,7,8)(H,9,10)/t4-;/m0./s1; Key:SLPUVFBNQHVEEU-WCCKRBBISA-N;
	(verify)

Ornithine oxoglutarate (OGO) or ornithine α-ketoglutarate (OKG) is a drug used in liver therapy. It is the salt formed from ornithine and alpha-ketoglutaric acid. It is also used to improve nutritional health in elderly patients.^[1]^[2]

References

^ Blonde-Cynober F, Aussel C, Cynober L (January 2003). "Use of ornithine alpha-ketoglutarate in clinical nutrition of elderly patients". Nutrition. 19 (1): 73–5. doi:10.1016/S0899-9007(02)00849-3. PMID 12507647.
^ Brocker P, Vellas B, Albarede JL, Poynard T (July 1994). "A two-centre, randomized, double-blind trial of ornithine oxoglutarate in 194 elderly, ambulatory, convalescent subjects". Age and Ageing. 23 (4): 303–6. doi:10.1093/ageing/23.4.303. PMID 7976777.

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[1] Blonde-Cynober F, Aussel C, Cynober L (January 2003). "Use of ornithine alpha-ketoglutarate in clinical nutrition of elderly patients". Nutrition. 19 (1): 73–5. doi:10.1016/S0899-9007(02)00849-3. PMID 12507647.

[2] Brocker P, Vellas B, Albarede JL, Poynard T (July 1994). "A two-centre, randomized, double-blind trial of ornithine oxoglutarate in 194 elderly, ambulatory, convalescent subjects". Age and Ageing. 23 (4): 303–6. doi:10.1093/ageing/23.4.303. PMID 7976777.

[1]

[2]

Clinical data

Ornithine (top) and ketoglutaric acid (bottom)
ATC code	A05BA06 (WHO)
Identifiers
IUPAC name 2-Oxopentanedioic acid - L-ornithine (1:1)
CAS Number	34414-83-0^Y
PubChem CID	78866
ChemSpider	71201
CompTox Dashboard (EPA)	DTXSID30958449 DTXSID20187988, DTXSID30958449
ECHA InfoCard	100.047.261 100.023.615, 100.047.261
Chemical and physical data
Formula	C₁₀H₁₈N₂O₇
Molar mass	278.261 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES C(C[C@@H](C(=O)O)N)CN.C(CC(=O)O)C(=O)C(=O)O
InChI InChI=1S/C5H12N2O2.C5H6O5/c6-3-1-2-4(7)5(8)9;6-3(5(9)10)1-2-4(7)8/h4H,1-3,6-7H2,(H,8,9);1-2H2,(H,7,8)(H,9,10)/t4-;/m0./s1 Key:SLPUVFBNQHVEEU-WCCKRBBISA-N
(verify)