The given name Orly may refer to:
- Orly Castel-Bloom (born 1960), Israeli author
- Orly Goldwasser, Israeli Egyptologist
- Orly Levy-Abekasis (born 1973), Israeli politician
- Orly Mercado (born 1946), Filipino politician and broadcast journalist
- Orly Orlyson (born 1983), Icelandic space entrepreneur
- Orly Silbersatz Banai (born 1957), Israeli actress
- Orly Taitz (born 1960), dentist and lawyer
- Orly Weinerman (born 1971), Israeli actress