OR51A7

Olfactory receptor 51A7 is a protein that in humans is encoded by the OR51A7 gene.

OR51A7
Identifiers
Aliases	OR51A7, OR11-27, olfactory receptor family 51 subfamily A member 7
External IDs	MGI: 3030410; HomoloGene: 45856; GeneCards: OR51A7; OMA:OR51A7 - orthologs
Gene location (Human) Chr. Chromosome 11 (human) Band 11p15.4 Start 4,903,783 bp End 4,909,462 bp
Gene location (Mouse) Chr. Chromosome 7 (mouse) Band 7|7 E3 Start 102,611,867 bp End 102,624,367 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in fundus prostate Top expressed in embryo adrenal gland More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 119687 258248 Ensembl ENSG00000176895 ENSMUSG00000073962 UniProt Q8NH64 n/a RefSeq (mRNA) NM_001004749 NM_001001805 RefSeq (protein) NP_001004749 n/a Location (UCSC) Chr 11: 4.9 – 4.91 Mb Chr 7: 102.61 – 102.62 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

Ligands

As of 2015, OR51A7 was an orphan receptor, meaning that no odorants have been identified which bind to it.

See also

• Olfactory receptor

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR51A7+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.