Michael Holt may refer to:
- Michael Holt (English footballer) (born 1977)
- Michael Holt (German footballer) (born 1986)
- Michael Holt (snooker player) (born 1978), English snooker player
- Michael Holt (musician) (born 1968), American musician
- Mister Terrific (Michael Holt), DC Comics superhero
- Michael Holt (author) (born 1929), British puzzle-book author