Masca is a village on the island of Tenerife, Spain.
Masca may also refer to:
- Mașca, a village in Iara, Romania
- Mâsca, a village in Șiria, Romania
- Masca (moth), a genus of moths in the family Erebidae
- Masca (shaman) , shaman women believed to possess healing powers in Piedmontese folklore