The limbus sign is a ring of dystrophic calcification evident as a "milky precipitate" (i.e. abnormal white color) at the corneal limbus. The corneal limbus is the part of the eye where the cornea (front/center) meets the sclera (white part of the eye). Thought to be caused by increased calcium concentration in the blood, this sign however persists after calcium phosphate concentration returns to normal.[1] Compare the limbus sign (calcification) with arcus senilis (lipid).[2]
Limbus sign | |
---|---|
Differential diagnosis | increased calcium concentration in the blood |
References
edit- ^ Orient, Dr. Jane M. (2011). Amazon Sapira's Art & Science of Bedside Diagnosis (Kindle Edition) Lippincott Williams & Wilkins. Retrieved January 7, 2012.
- ^ Edwards, Mark E. (2008). Geriatric physical diagnosis: a guide to observation and assessment. McFarland & Company. p. 96. Retrieved January 7, 2012.