As a surname, Lie may refer to
- A Norwegian surname Lie, which may refer to:
- Anders Danielsen Lie, Norwegian actor
- Jonas Lie (government minister), Norwegian councillor of state
- Jonas Lie (painter), Norwegian-American painter
- Jonas Lie (writer), Norwegian novelist
- Sophus Lie, Norwegian mathematician
- Trygve Lie, Norwegian politician, first Secretary-General of the United Nations
- Haakon Lie, Norwegian politician
- Kaare Lie, Norwegian footballer and journalist
- Niels Lie, Danish chess player
- Reidar Lie, Norwegian philosopher
- The common Hokkien transcription of Chinese surname Li (李), spelled Lie (Pe̍h-ōe-jī: Lí) in Indonesia and Netherlands:
- Lie Kim Hok, peranakan Chinese writer, social worker
- Lie Tek Swie, Indonesian film director
- Lie Tjeng Tjoan, Indonesian navy commander during the Indonesian National Revolution
- Lie Kiat Teng, Indonesian doctor and politician