The latent TGF-beta binding proteins (LTBP) are a family of carrier proteins.[1][2]
LTBP is a family of secreted multidomain proteins that were originally identified by their association with the latent form of transforming growth factors. They interact with a variety of extracellular matrix proteins and may play a role in the regulation of TGF beta bioavailability.
Genes
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References
edit- ^ Rifkin DB (March 2005). "Latent transforming growth factor-beta (TGF-beta) binding proteins: orchestrators of TGF-beta availability". J. Biol. Chem. 280 (9): 7409–12. doi:10.1074/jbc.R400029200. PMID 15611103.
- ^ Todorovic V, Jurukovski V, Chen Y, Fontana L, Dabovic B, Rifkin DB (January 2005). "Latent TGF-beta binding proteins". Int. J. Biochem. Cell Biol. 37 (1): 38–41. doi:10.1016/j.biocel.2004.03.011. PMID 15381147.
External links
edit- Latent+TGF-beta+Binding+Proteins at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
- PDBe-KB provides an overview of all the structure information available in the PDB for Human Latent-transforming growth factor beta-binding protein 1
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