LINGO2

LINGO2
Identifiers
Aliases	LINGO2, LERN3, LRRN6C, leucine rich repeat and Ig domain containing 2
External IDs	OMIM: 609793; MGI: 2442298; HomoloGene: 17621; GeneCards: LINGO2; OMA:LINGO2 - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	28,670,286 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	36,951,747 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; endothelial cell; ; middle temporal gyrus; ; Brodmann area 23; ; testicle; ; buccal mucosa cell; ; primary visual cortex; ; tail of epididymis; ; myometrium; ; body of uterus;
	Top expressed in
	zygote; ; secondary oocyte; ; piriform cortex; ; respiratory epithelium; ; olfactory epithelium; ; dentate gyrus of hippocampal formation granule cell; ; primary visual cortex; ; superior frontal gyrus; ; ventromedial nucleus; ; primary motor cortex;
	More reference expression data
	n/a
Orthologs
	158038
	242384
	ENSG00000174482
	ENSMUSG00000045083
	Q7L985
	Q3URE9
	NM_001258282; NM_152570; NM_001354574; NM_001354575
	NM_001165999; NM_001166000; NM_001166001; NM_175516
	NP_001245211; NP_689783; NP_001341503; NP_001341504
	NP_001159471; NP_001159472; NP_001159473; NP_780725
	Wikidata
View/Edit Human	View/Edit Mouse

Leucine rich repeat and Ig domain containing 2 is a protein that in humans is encoded by the LINGO2 gene. ^[5]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000174482 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000045083 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Leucine rich repeat and Ig domain containing 2". Retrieved 2014-03-31.

Ferreira RC, Pan-Hammarström Q, Graham RR, Gateva V, Fontán G, Lee AT, et al. (September 2010). "Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency". Nature Genetics. 42 (9): 777–780. doi:10.1038/ng.644. PMID 20694011. S2CID 205356843.
Wu YW, Prakash KM, Rong TY, Li HH, Xiao Q, Tan LC, et al. (June 2011). "Lingo2 variants associated with essential tremor and Parkinson's disease". Human Genetics. 129 (6): 611–615. doi:10.1007/s00439-011-0955-3. PMID 21287203. S2CID 23493765.
Su FC, Chen CM, Chen YC, Wu YR (June 2012). "LINGO-2 polymorphism and the risk of Parkinson's disease in Taiwan". Parkinsonism & Related Disorders. 18 (5): 609–611. doi:10.1016/j.parkreldis.2011.11.013. PMID 22123311.
Ichikawa S, Koller DL, Padgett LR, Lai D, Hui SL, Peacock M, et al. (August 2010). "Replication of previous genome-wide association studies of bone mineral density in premenopausal American women". Journal of Bone and Mineral Research. 25 (8): 1821–1829. doi:10.1002/jbmr.62. PMC 3153352. PMID 20200978.
Vilariño-Güell C, Wider C, Ross OA, Jasinska-Myga B, Kachergus J, Cobb SA, et al. (October 2010). "LINGO1 and LINGO2 variants are associated with essential tremor and Parkinson disease". Neurogenetics. 11 (4): 401–408. doi:10.1007/s10048-010-0241-x. PMC 3930084. PMID 20369371.
Carim-Todd L, Escarceller M, Estivill X, Sumoy L (December 2003). "LRRN6A/LERN1 (leucine-rich repeat neuronal protein 1), a novel gene with enriched expression in limbic system and neocortex". The European Journal of Neuroscience. 18 (12): 3167–3182. doi:10.1111/j.1460-9568.2003.03003.x. PMID 14686891. S2CID 42086715.

This article on a gene on human chromosome 9 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000174482 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000045083 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Leucine rich repeat and Ig domain containing 2". Retrieved 2014-03-31.

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[4]

LINGO2

References

Further reading