Khachaturian, Khachaturyan, Khachadurian or Khachatourian (Armenian: Խաչատուրյան) is an Armenian surname meaning "cross bearer". People with the name include the following:
- Andrey Khachaturyan (born 1987), Belarusian footballer
- Aram Khachaturian (1903–1978), Soviet Armenian composer
- Artur Khachaturyan (born 1992), Armenian basketball player
- Emin Khachaturian (1930–2000), Armenian conductor and composer
- Gayane Khachaturian (1942–2009), Soviet and Armenian painter
- Karen Khachaturian (1920–2011), Soviet and Russian composer
- Leon Khachatourian (born 1936), Iranian Armenian boxer
- Ontronik Khachaturian (born 1975), American musician
- Vahagn Khachaturyan (born 1959), Armenian politician