Karthika Deepam is a Hindu festival of lights in southern India, related to Diwali.
Karthika Deepam may also refer to:
- Karthika Deepam (film), an Indian Telugu-language film
- Karthika Deepam (Telugu TV series), a 2017 Indian Telugu-language TV series
- Karthika Deepam (Malayalam TV series), a 2020 Indian Malayalam-language TV series