Iocarmic acid

Iocarmic acid
Clinical data
Trade names	Dimer-X
Other names	3-[[6-[[3-Carboxy-2,4,6-triiodo-5-(methylcarbamoyl)phenyl]amino]-6-oxohexanoyl]amino]-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid
ATC code	V08AA08 (WHO) ;
Identifiers
	IUPAC name 3-(5-{[3-carboxy-2,4,6-triiodo-5-(methylcarbamoyl)phenyl]carbamoyl}pentanamido)-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid;
CAS Number	10397-75-8 ;
PubChem CID	25229;
DrugBank	DB13755 ;
ChemSpider	23564 ;
UNII	82PB24K6TZ;
KEGG	D01099 ;
CompTox Dashboard (EPA)	DTXSID7023148 ;
ECHA InfoCard	100.030.771
Chemical and physical data
Formula	C24H20I6N4O8
Molar mass	1253.871 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CNC(=O)c1c(c(c(c(c1I)NC(=O)CCCCC(=O)Nc2c(c(c(c(c2I)C(=O)O)I)C(=O)NC)I)I)C(=O)O)I;
	InChI InChI=1S/C24H20I6N4O8/c1-31-21(37)9-13(25)11(23(39)40)17(29)19(15(9)27)33-7(35)5-3-4-6-8(36)34-20-16(28)10(22(38)32-2)14(26)12(18(20)30)24(41)42/h3-6H2,1-2H3,(H,31,37)(H,32,38)(H,33,35)(H,34,36)(H,39,40)(H,41,42) ; Key:SMQYOVYWPWASGU-UHFFFAOYSA-N ;
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Iocarmic acid (trade name Dimer-X) is a pharmaceutical drug used as an iodinated contrast medium for X-ray imaging in the 1970s and 80s. Uses included imaging of the uterus and fallopian tubes. It was applied in form of its salt, meglumine iocarmate.^[1]^[2]

It is not known to be marketed anywhere in the world in 2021.

References

^ Schütte HE (1982). "Comparative study: Endografine (diatrizoate), Vasurix polyvidone (acetrizoate), Dimer-X (iocarmate) and Hexabrix (ioxaglate) in hysterosalpingography". Diagnostic Imaging. 51 (6): 277–83. PMID 7173007.
^ Van Dellen JR, Lipschitz R (October 1973). "Meglumine iocarmate (Dimer-X) ventriculography". Clinical Radiology. 24 (4): 449–52. doi:10.1016/s0009-9260(73)80146-1. PMID 4621055.

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[1] Schütte HE (1982). "Comparative study: Endografine (diatrizoate), Vasurix polyvidone (acetrizoate), Dimer-X (iocarmate) and Hexabrix (ioxaglate) in hysterosalpingography". Diagnostic Imaging. 51 (6): 277–83. PMID 7173007.

[2] Van Dellen JR, Lipschitz R (October 1973). "Meglumine iocarmate (Dimer-X) ventriculography". Clinical Radiology. 24 (4): 449–52. doi:10.1016/s0009-9260(73)80146-1. PMID 4621055.

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