Interleukin 12 receptor is a type I cytokine receptor, binding interleukin 12 and consisting of beta 1[1] and beta 2 subunits.[2]
| interleukin 12 receptor, beta 1 | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | IL12RB1 | ||||||
| Alt. symbols | IL12RB, CD212 | ||||||
| NCBI gene | 3594 | ||||||
| HGNC | 5971 | ||||||
| OMIM | 601604 | ||||||
| RefSeq | NM_005535 | ||||||
| UniProt | P42701 | ||||||
| Other data | |||||||
| Locus | Chr. 19 p13.1 | ||||||
| |||||||
| beta 2 subunit, interleukin 12 receptor, beta 2 | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | IL12RB2 | ||||||
| NCBI gene | 3595 | ||||||
| HGNC | 5972 | ||||||
| OMIM | 601642 | ||||||
| RefSeq | NM_001559 | ||||||
| UniProt | Q99665 | ||||||
| Other data | |||||||
| Locus | Chr. 1 p31.3-31.2 | ||||||
| |||||||
References
edit- ^ Chua AO, Chizzonite R, Desai BB, Truitt TP, Nunes P, Minetti LJ, Warrier RR, Presky DH, Levine JF, Gately MK (1994). "Expression cloning of a human IL-12 receptor component. A new member of the cytokine receptor superfamily with strong homology to gp130". J. Immunol. 153 (1): 128–36. doi:10.4049/jimmunol.153.1.128. PMID 7911493. S2CID 9211163.
- ^ Presky DH, Yang H, Minetti LJ, Chua AO, Nabavi N, Wu CY, Gately MK, Gubler U (1996). "A functional interleukin 12 receptor complex is composed of two beta-type cytokine receptor subunits". Proc. Natl. Acad. Sci. U.S.A. 93 (24): 14002–14007. Bibcode:1996PNAS...9314002P. doi:10.1073/pnas.93.24.14002. PMC 19484. PMID 8943050.
External links
edit- Receptors,+Interleukin-12 at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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