The compilation album is the band's second greatest hits package. It was released 23 years after the first greatest hits package in 1988. The album includes the remaining radio hits that were left off the first greatest hits package and fan favorites. This includes "Stone in Love", "Feeling That Way", "Anytime", "Just the Same Way", "Still They Ride", "Suzanne", "Walks Like a Lady", "The Party's Over" and "After the Fall".
Greatest Hits 2 was released on CD, digital download and in a gatefold double-vinyl edition. The songs were re-mastered to vinyl by Robert Hadley and former lead singer of Journey, Steve Perry. Perry said of the mastering: "I truly forgot how sonically exciting and just plain better these Journey tracks sound back where they originally lived...on vinyl. The stereo separation, the center imaging and the sonic depth of the tracks themselves is more true to what we all loved about these original final mixes. All the instruments and voices, to me personally, sound so damn good that all I want to do is reach for the volume and turn it up!".[3]
The album was supposed to include "The Eyes of a Woman" but by request by lead guitarist Neal Schon, it was replaced by "Little Girl".[4] Neal Schon's father, jazz musician Matthew Schon worked with the band on "Little Girl".[3]
Greatest Hits I & II is a repackaging of both of Journey’s Greatest Hits albums. Originally released in 2011, it was reissued in Japan in both 2013 and 2017 with different cover art.