Endemixit is a project that studies the effects of reduced population size in five Italian endemic species at risk of extinction. The final objective is to estimate the risk of extinction from genomic data and contribute to the preservation of these species.[1] The project was funded by the MUR (Italian Ministry for Research) and coordinated by the Department of Life Sciences and Biotechnology of the University of Ferrara with the involvement of five other Italian universities: Ancona, Florence, Padua, Rome Tor Vergata and Trieste.[2][3]
Species under study
editThe species considered are all classified in danger or in critical danger of extinction in the IUCN Red List:
- Podarcis raffonei (Aeolian wall lizard), a lizard with a current range restricted to three Aeolian Islands and subdivided into isolated and relatively distant populations.[4]
- Hipparchia sbordonii (Ponza grayling), currently only found on some Pontine Islands.[5]
- Acipenser naccarii (Adriatic sturgeon), once widespread in the Northern Adriatic Sea and in many rivers of Northern Italy, but today almost extinct in nature.[6]
- Bombina pachypus (Apennine yellow-bellied toad), an endemic and endangered species of the Italian Peninsula closely related to the most common European yellow-bellied toad (B. variegata).[7]
- Ursus arctos marsicanus (Marsican, or Apennine, brown bear), a subspecies of brown bear (U. arctos), present exclusively in a small region of the central Apennines Mountains.[8]
Applications and innovative aspects
editEndemixit is a genomic project applied to the conservation of biodiversity.[9][10] Five reference genomes will be produced (one for each endemic species/subspecies), and 20 to 30 individuals per species will be re-sequenced (whole genomes at intermediate coverage). Population genomics analyses will be used to reconstruct past demographic processes and to estimate the genetic load possibly accumulated due to genetic drift. The results will be theoretically important to understand the genetic load dynamic.[11] Practically, they will provide guidelines and priorities for the conservation of these endemics.[12]
Endemixit is a partner of the European Reference Genome Atlas (ERGA), a pan-European consortium that aims to produce reference genomes of high quality for all European biodiversity to contribute to the protection of the same.[13] Endemixit is also affiliated to the Earth Biogenome Project (EBP), an international project that aims to sequence the complete genome of all eukaryotic living beings in 10 years.[14]
References
edit- ^ Fronte, Margherita (March 2021). "Io ti salverò col tuo DNA". Focus. 441: 70–73.
- ^ Di Bisceglie, Federico (18 September 2020). "Dal rospetto ululone all'orso bruno Studio di Unife sulle specie a rischio".
- ^ Redazione; Redazione (2020-08-21). "Pikaia – Farfalle, orsi e altri endemismi: il progetto EndemixIT". Pikaia (in Italian). Retrieved 2022-09-01.
- ^ Corti, Claudia; Pérez-Mellado, Valentin; Sindaco, Roberto; Romano, Antonio (14 December 2008). "Podarcis raffonei". doi:10.2305/iucn.uk.2009.rlts.t61552a12514822.en.
{{cite journal}}: Cite journal requires|journal=(help) - ^ van Swaay, C., Wynhoff, I., Wiemers, M., Katbeh-Bader, A., Power, A., Benyamini, D., Tzirkalli, E., Balletto, E., Monteiro, E., Karaçetin, E., Franeta, F., Pe'er, G., Welch, H., Thompson, K., Pamperis, L., Dapporto, L., Šašić, M., López Munguira, M., Micevski, N., Dupont, P., Garcia-Pereira, P., Moulai, R., Caruana, R., Verovnik, R., Bonelli, S. & Beshkov, S. (28 February 2013). "Hipparchia sbordonii". doi:10.2305/iucn.uk.2015-2.rlts.t173231a64640021.en.
{{cite journal}}: Cite journal requires|journal=(help)CS1 maint: multiple names: authors list (link) - ^ Bronzi, P., Congiu, L., Rossi, R., Zerunian, S. & Arlati, G. (24 October 2009). "Acipenser naccarii". doi:10.2305/iucn.uk.2011-1.rlts.t224a175973332.en.
{{cite journal}}: Cite journal requires|journal=(help)CS1 maint: multiple names: authors list (link) - ^ Andreone, F., Corti, C., Sindaco, R., Romano, A., Giachi, F., Vanni, S. & Delfino, G. (14 December 2008). "Bombina pachypus". doi:10.2305/iucn.uk.2009.rlts.t54450a11147957.en.
{{cite journal}}: Cite journal requires|journal=(help)CS1 maint: multiple names: authors list (link) - ^ Ciucci, Paolo; Boitani, Luigi (November 2008). "The Apennine Brown Bear: A Critical Review of Its Status and Conservation Problems". Ursus. 19 (2): 130–145. doi:10.2192/07PER012.1. ISSN 1537-6176. S2CID 55877575.
- ^ "Biodiversità, la ricchezza che stiamo perdendo". Focus.it. Retrieved 2022-09-01.
- ^ "The project". ENDEMIXIT. 2020-04-11. Retrieved 2022-09-01.
- ^ Bertorelle, Giorgio; Raffini, Francesca; Bosse, Mirte; Bortoluzzi, Chiara; Iannucci, Alessio; Trucchi, Emiliano; Morales, Hernán E.; van Oosterhout, Cock (August 2022). "Genetic load: genomic estimates and applications in non-model animals". Nature Reviews Genetics. 23 (8): 492–503. doi:10.1038/s41576-022-00448-x. hdl:1871.1/d9d2b4fc-9ae2-4c6d-b9ad-88cc12c32112. ISSN 1471-0064. PMID 35136196. S2CID 246678376.
- ^ "Ululone & C: cinque animali italiani da salvare". la Repubblica (in Italian). 2021-11-19. Retrieved 2022-09-01.
- ^ "A genome atlas of european biodiversity". erga. Retrieved 2022-09-01.
- ^ "Earth BioGenome Project". Earth BioGenome Project. Retrieved 2022-09-01.