Ebalzotan

Ebalzotan
Clinical data
Routes of; administration	Oral
ATC code	none;
Legal status
Legal status	In general: uncontrolled;
Identifiers
	IUPAC name (3R)-N-(propan-2-yl)-3-[propan-2-yl(propyl)amino]-3,4-dihydro-2H-chromene-5-carboxamide;
CAS Number	149494-37-1;
PubChem CID	9797080;
ChemSpider	7972846;
UNII	WV4B56N49H;
ChEMBL	ChEMBL1742470;
CompTox Dashboard (EPA)	DTXSID601029378 ;
Chemical and physical data
Formula	C19H30N2O2
Molar mass	318.461 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(NC(C)C)c2cccc1OC[C@H](N(C(C)C)CCC)Cc12;

Ebalzotan (NAE-086) is a selective 5-HT_1A receptor agonist.^[1]^[2] It was under development as an antidepressant and anxiolytic agent but produced undesirable side effects in phase I clinical trials and was subsequently discontinued.^[1]^[2]

References

Clinical data

Routes of administration	Oral
ATC code	none
Legal status
Legal status	In general: uncontrolled
Identifiers
IUPAC name (3R)-N-(propan-2-yl)-3-[propan-2-yl(propyl)amino]-3,4-dihydro-2H-chromene-5-carboxamide
CAS Number	149494-37-1
PubChem CID	9797080
ChemSpider	7972846
UNII	WV4B56N49H
ChEMBL	ChEMBL1742470
CompTox Dashboard (EPA)	DTXSID601029378
Chemical and physical data
Formula	C₁₉H₃₀N₂O₂
Molar mass	318.461 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O=C(NC(C)C)c2cccc1OC[C@H](N(C(C)C)CCC)Cc12