Dihydrochalcone

Dihydrochalcone (DHC) is the organic compound with the formula C₆H₅C(O)(CH₂)₂C₆H₅. It is the reduced derivative of chalcone (C₆H₅C(O)(CH)₂C₆H₅). It is a white solid that is soluble in many organic solvents. Dihydrochalcone per se is often minor significance, but some derivatives occur in nature and have attracted attention as drugs.

Dihydrochalcone

Names
Preferred IUPAC name 1,3-Diphenylpropan-1-one
Other names Hydrochalcone Benzylacetophenone Hydrocinnamophenone 3-Phenylpropiophenone Phenethyl phenyl ketone Phenyl phenethyl ketone β-Phenylpropiophenone 1,3-Diphenyl-1-propanone ω-Benzyl acetophenone
Identifiers
CAS Number	1083-30-3 Y=
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL490512 Y
ChemSpider	58334 Y
ECHA InfoCard	100.150.317
PubChem CID	64802
UNII	H5W525SX7Q Y
CompTox Dashboard (EPA)	DTXSID7061481
InChI InChI=1S/C15H14O/c16-15(14-9-5-2-6-10-14)12-11-13-7-3-1-4-8-13/h1-10H,11-12H2 Y Key: QGGZBXOADPVUPN-UHFFFAOYSA-N Y
SMILES C1=CC=C(C=C1)CCC(=O)C2=CC=CC=C2
Properties
Chemical formula	C15H14O
Molar mass	210.27 g/mol
Appearance	white solid
Density	1.0614 g/cm3
Melting point	72–75 °C (162–167 °F; 345–348 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Y verify (what is YN ?) Infobox references

Natural dihydrochalcones

Neohesperidin dihydrochalcone is a commercial artificial sweetener that features the dihydrochalcone substituent.

• Aspalathin, a C-linked dihydrochalcone glucoside found in rooibos, a common herbal tea
• Naringin dihydrochalcone, an artificial sweetener derived from naringin
• Neohesperidin dihydrochalcone, an artificial sweetener derived from citrus
• Nothofagin, a C-linked phloretin glucoside found in rooibos
• Phloretin
• Isosalipurpurin

Dihydrochalcones (3′,5′-dihydroxy-2′,4′,6′-trimethoxydihydrochalcone (methyl linderone) and 2′-hydroxy-3′,4′,5′,6′-tetramethoxydihydrochalcone (dihydrokanakugiol) can be found in twigs of Lindera lucida.