ConoServer is a database of toxins that are expressed by the predatory sea snails in the family Conidae, the cone snails. These toxins are known as conotoxins or conopeptides.[1] The toxins are of importance to medical research. A notable feature of these peptides is their high specificity and affinity towards human ion channels, receptors and transporters of the nervous system. This makes conopeptides an interesting resource for the physiological studies of neuroreceptors and promising drug leads.
 | |
| Content | |
|---|---|
| Description | conopeptide database. |
| Organisms | cone snails |
| Contact | |
| Research center | University of Queensland |
| Laboratory | Division of Chemistry and Structural Biology, Institute for Molecular Bioscience |
| Primary citation | Kaas & al. (2012)[1] |
| Release date | 2008 |
| Access | |
| Website | http://www.conoserver.org |
| Miscellaneous | |
| Curation policy | manual/automatic |
See also
editReferences
edit- ^ a b Kaas, Quentin; Yu Rilei; Jin Ai-Hua; Dutertre Sébastien; Craik David J (Jan 2012). "ConoServer: updated content, knowledge, and discovery tools in the conopeptide database". Nucleic Acids Res. 40 (Database issue). England: D325-30. doi:10.1093/nar/gkr886. PMC 3245185. PMID 22058133.
External links
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