Benoît Roux is an Amgen Professor of Biochemistry and Molecular Biophysics at the University of Chicago. He has previously taught at University of Montreal and Weill Medical College of Cornell University. Benoît Roux was a recipient of the 1998 Rutherford Memorial Medal in Chemistry, awarded by the Royal Society of Canada.[2]
Benoît Roux | |
|---|---|
| Nationality | Canadian |
| Alma mater | University of Montreal Harvard University[1] |
| Awards | Rutherford Memorial Medal Fellow of the Biophysical Society of Canada Fellow of the Royal Society of Canada |
| Scientific career | |
| Fields | Biophysics |
| Institutions | University of Montreal Cornell University University of Chicago |
| Thesis | Theoretical Study of Ion Transport in the Gramicidin A Channel (1990) |
| Doctoral advisor | Martin Karplus |
| Website | http://thallium.bsd.uchicago.edu/ |
Life and career
editRoux obtained B.Sc. and M.Sc. in physics from the University of Montreal in 1981 and 1984 respectively. He completed his Ph.D. at Harvard University under the supervision of Martin Karplus, graduating in 1990. He served at the French Alternative Energies and Atomic Energy Commission from 1991 to 1992 and was a Foreign Research Fellow at the Centre D’Etudes. He was a faculty member in the department of physics at the Université de Montréal until 1999, when he relocated to Weill Cornell Medicine. He relocated to the department of biochemistry and molecular biology at the University of Chicago in 2005. He also serves as a research scientist at the Center for Nanoscale Materials, a department of the Argonne National Laboratory.[3] He is an accomplished classical pianist, specializing in the work of Frédéric Chopin.
Research
editHis laboratory at the University of Chicago mostly uses theoretical techniques, such as classical molecular dynamics, to understand the functioning of biological systems at the molecular level. His research has investigated structure, dynamics, and the function of biological macromolecular systems such as ion channels, receptors, and protein kinases.[4]
He is a pioneer in the study of membrane proteins using molecular dynamics with explicit phospholipid molecules and solvent.[5][6] His laboratory has also developed novel computational methods to improve efficiency and applicability of theoretical investigations to molecular recognition phenomena. His work has bridged theory and experiment in biophysics by employing ever-increasing computational power to further the understanding of the molecular basis of life.
Works
editIn 1996, he co-authored Biological Membranes: A Molecular Perspective from Computation and Experiment with Kenneth M. Merz.[7] In 2001, he co-edited a book with Oren M. Becker, Alexander D. MacKerell Jr., Benoit Roux, Masakatsu Watanabe, ``Computational Biochemistry and Biophysics. [8] In 2021, he authored a text on biophysical theory and simulations, Computational Modeling and Simulations of Biomolecular Systems.[9]
Honors, awards, and fellowships
edit- Journal of Computational Chemistry: Special Issue on Membrane Protein Simulations and Free Energy Approaches in honor of Professor Benoit Roux's 60th birthday[10]
- Rutherford Memorial Medal, Royal Society of Canada (1998)[11]
- Fellow of the Biophysical Society of Canada (2017)[12]
- Fellow of the Royal Society of Canada (2021)[13]
- Fellow of the American Association for the Advancement of Science (2024)[14]
- Kenneth S. Cole Award from the Channels, Receptors & Transporters Subgroup of the Biophysical Society (2024)
- John D. Ferry Lectureship in Macromolecular Science - UW Madison (2024)
References
edit- ^ "Department of Biochemistry & Molecular Biology". Archived from the original on 2016-01-24.
- ^ "Faculty members receive named, distinguished service professorships". University of Chicago. January 27, 2015. Retrieved May 11, 2019.
- ^ "Benoît Roux". University of Chicago. Retrieved March 11, 2019.
- ^ "Benoît Roux". University of Chicago. Retrieved May 11, 2019.
- ^ Ion transport in a model gramicidin channel. Structure and thermodynamics. B. Roux and M. Karplus Biophys. J. 1991;59(5):961-981.
- ^ Theoretical and computational models of ion channels. B. Roux Curr Opin Struct Biol. 2002;12(2):182-189.
- ^ Merz, Kenneth M.; Roux, Benoît (1996). Biological Membranes: A Molecular Perspective from Computation and Experiment. Birkhäuser. doi:10.1007/978-1-4684-8580-6. ISBN 1468485806. S2CID 30908633.
- ^ ROUX, BENOIT (2001). Becker, Oren M.; MacKerell Jr., Alexander D.; Roux, Benoit; Watanabe, Masakatsu (eds.). Computational Biochemistry and Biophysics. Taylor Francis. doi:10.1201/9780203903827. ISBN 978-0-203-90382-7.
- ^ ROUX, BENOIT (2021). COMPUTATIONAL MODELING AND SIMULATIONS OF BIOMOLECULAR SYSTEMS : simulations of... biomolecular systems. [S.l.]: WORLD SCIENTIFIC PUB. doi:10.1142/12173. ISBN 978-981-12-3275-6. OCLC 1225976875.
- ^ "Special Issue: Membrane Protein Simulations and Free Energy Approaches: In honor of Professor Benoit Roux's 60th birthday". Journal of Computational Chemistry. 41 (5): C1, 379–481. February 15, 2020. Retrieved 30 June 2020.
- ^ "Past Award Winners". Royal Society of Canada. 21 October 2018. Retrieved May 11, 2019.
- ^ Christoff, Craig (April 19, 2017). "2017 Fellow of the BSC: Dr. Benoît Roux". Biophysical Society of Canada. Retrieved May 11, 2019.
- ^ Wood, Matt (2021-09-08). "Benoit Roux, PhD, elected to the Royal Society of Canada". Science Life | Biological Sciences Division Research News. Retrieved 2021-09-13.
- ^ "Two UChicago scholars elected as 2023 American Association for the Advancement of Science fellows". news.uchicago.edu. 2024-04-18. Retrieved 2024-04-18.
External links
edit- Benoît Roux publications indexed by Google Scholar
- Web page in the Biochemistry Department [1]