Aprobarbital (or aprobarbitone), sold under the brand names Oramon, Somnifaine, and Allonal, is a barbiturate derivative invented in the 1920s by Ernst Preiswerk. It has sedative, hypnotic, and anticonvulsant properties, and was used primarily for the treatment of insomnia.[2] Aprobarbital was never as widely used as more common barbiturate derivatives such as phenobarbital and is now rarely prescribed. It has been largely replaced by newer drugs with a better safety margin.
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| Trade names | Oramon, Somnifane, Allonal |
| Other names | aprobarbitone, allylpropymal, Alurate, 5-isopropyl- 5-allylbarbituric acid |
| AHFS/Drugs.com | International Drug Names |
| Drug class | Barbiturate |
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| ECHA InfoCard | 100.000.908 |
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| Formula | C10H14N2O3 |
| Molar mass | 210.233 g·mol−1 |
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See also
editReferences
edit- ^ Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-16.
- ^ Reddemann H, Türk E (May 1966). "[Oramon poisoning in infancy and childhood. Observations on 12 aprobarbital poisonings]". Das Deutsche Gesundheitswesen (in German). 21 (19): 878–81. PMID 5973760.
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