4-Thiouridine is an atypical nucleoside formed with the 4-thiouracil base found in transfer RNA (tRNA).[1] Its biosynthesis has been determined.[2]
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Preferred IUPAC name
1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-sulfanylidene-3,4-dihydropyrimidin-2(1H)-one | |
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3D model (JSmol)
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ChEBI | |
ChemSpider | |
ECHA InfoCard | 100.034.291 |
EC Number |
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MeSH | Thiouridine |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C9H12N2O5S | |
Molar mass | 260.26 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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References
edit- ^ Alberts, Bruce (18 November 2014). Molecular biology of the cell (Sixth ed.). New York, NY. p. 337. ISBN 978-0-8153-4432-2. OCLC 887605755.
{{cite book}}
: CS1 maint: location missing publisher (link) - ^ Park, Chung-Min; Weerasinghe, Laksiri; Day, Jacob J.; Fukuto, Jon M.; Xian, Ming (2015). "Persulfides: Current knowledge and challenges in chemistry and chemical biology". Molecular BioSystems. 11 (7): 1775–1785. doi:10.1039/c5mb00216h. PMC 4470748. PMID 25969163.