A Zahn infarct is a pseudo-infarction of the liver, consisting of an area of congestion with parenchymal atrophy but no necrosis, and usually due to obstruction of a branch of the portal vein.[1][2] Zahn infarcts are unique in that there is collateral congestion of liver sinusoids that do not include areas of anoxia seen in most infarcts. Fibrotic tissue may develop in the area of the infarct and it could be caused by an occlusive phlebitis in portal vein radicles.[3]
| Zahn infarct | |
|---|---|
| Specialty | Hepatology |
Signs and symptoms
editZahn's infarct don't have any specific symptoms.[4]
Diagnosis
editHistopathology reveals severe sinusoidal congestion, which is most noticeable at the lobule centers, as well as liver cell atrophy.[4]
Eponym
editThe Zahn infarct is named for Friedrich Wilhelm Zahn.[1]
References
edit- ^ a b Stegman, JK, ed. (2006), Stedman's Medical Dictionary (28th ed.), Baltimore, MD: Lippincott, Williams, & Wilkins
- ^ "GDPR page".
- ^ Matsumoto T, Kuwabara N, Abe H, Fukuda Y, Suyama M, Fujii D, Kojima K, Futagawa S (1992), "Zahn infarct of the liver resulting from occlusive phlebitis in portal vein radicles", American Journal of Gastroenterology, 87 (3): 365–368, PMID 1539574
- ^ a b Horrocks, P.; Tapp, E. (September 1, 1966). "Zahn's 'infarcts' of the liver". Journal of Clinical Pathology. 19 (5). BMJ: 475–478. doi:10.1136/jcp.19.5.475. ISSN 0021-9746. PMC 473353. PMID 5919359.
Further reading
edit- Zimmermann, Arthur (2016). "Tumor-like Necroses of the Liver: Liver Infarct and Hepatic Pseudo-infarct (Zahn's Infarct)". Tumors and Tumor-Like Lesions of the Hepatobiliary Tract. Cham: Springer International Publishing. pp. 1–9. doi:10.1007/978-3-319-26587-2_137-1. ISBN 978-3-319-26587-2.