Indigenous peoples of South America have been involved in several wars of different scale and nature. Conflicts with Iberoamerican states and between different Indigenous groups have decreased over time.
- Battle of the Maule
- Inca Civil War (1525–1527)
- Spanish conquest of the Inca Empire (1532–1572)
- Arauco War (1536- ~1800)
- Guaraní War (1756)
- Rebellion of Túpac Amaru II (1780–1782)
- Chilean War of Independence (1810–1822)
- Occupation of Araucanía (1861–1884)
- Conquest of the Desert (1872–1884)
- Mapuche conflict (1990–Present)