Content to Unethical human experimentation in the United States

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In May 2004, a young man named Dan Markingson committed suicide in a controversial AstraZeneca-funded study of atypical antipsychotics conducted by the University of Minnesota Department of Psychiatry. Markingson had been recruited into the study while acutely psychotic after he had been placed under an involuntary commitment order, the terms of which instructed him to obey the treatment orders of his psychiatrist. His mother, Mary Weiss, had objected to his recruitment into the study and attempted for months to have him released, warning that his condition was deteriorating and that he was in danger of committing suicide.[1] In 2010 a group of University of Minnesota faculty members wrote a public letter to the Board of Regents requesting an investigation of Markingson's death. The letter outlined a series of ethical violations, including financial conflicts of interest on the part of the researchers, the inability of Markingson to give informed consent, improper financial incentives for enrolling subjects, and the questionable scientific value of the study.[2] University of Minnesota officials have denied any wrongdoing.

Thank you for contributing this, referencing it, and formatting it according to Wikipedia standards. However, I do not think this article is the place for this. The other examples in that article set major precedent and were extensively covered in academic literature. I am not sure where this case could go. Adding it to the queue at list of medical ethics cases might be more appropriate. If you want to talk more then I am would happy to help. Thanks for coming to Wikipedia - I hope that you stay around. Blue Rasberry (talk) 01:46, 3 December 2012 (UTC)Reply

Thanks for your comment (and your patience.) I think the Markingson case may have received more academic attention than you think. You can find it discussed in IRB Advisor, for example, and in Elliott's White Coat, Black Hat.

http://connection.ebscohost.com/c/articles/33725224/conflict-interest-issues-raised-by-subjects-suicide

http://www.amazon.com/White-Coat-Black-Hat-Adventures/dp/0807061425

Also, the case resulted in a change in Minnesota law so that psychiatrists are now banned from recruiting patients under an involuntary commitment order into psychiatric drug studies.

https://www.revisor.mn.gov/statutes/?id=253B.095&format=pdf

The case has also been discussed in academic sessions at meetings of Public Responsibility in Medicine and Research, the American Association of Bioethics and Humanities, Pharmed Out, and the Australasian Association of Bioethics and Health Law.

Also, while many of the examples on this page have indeed received a substantial amount of attention from academics and policymakers, quite a few have only been reported in the press or in a single book (for example, some of the examples cited in Goliszek's In The Name of Science.)

RMNixon1972 (talk) 13:39, 3 December 2012 (UTC)Reply

Okay, I replaced the content you added and posted some other thoughts on the article's talk page. Thanks. Blue Rasberry (talk) 14:23, 3 December 2012 (UTC)Reply

Thanks, and thanks again for your patience. RMNixon1972 (talk) 14:33, 3 December 2012 (UTC)Reply

Welcome!

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Hello, RMNixon1972, and welcome to Wikipedia! Thank you for your contributions, especially what you did for Unethical human experimentation in the United States. I hope you like the place and decide to stay. Here are some pages that you might find helpful:

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RMNixon1972, you are invited to the Teahouse

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Your submission at Articles for creation

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Wikipedia talk:Articles for creation/Dan Markingson concern

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Your draft article, Wikipedia talk:Articles for creation/Dan Markingson

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Hello RMNixon1972. It has been over six months since you last edited your WP:AFC draft article submission, entitled "Dan Markingson".

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  1. ^ Elliott, Carl (September–October 2012). "The Deadly Corruption of Clinical Trials". Mother Jones. Retrieved 2 December 2012.{{cite news}}: CS1 maint: date format (link)
  2. ^ Perry, Susan (December 6, 2012). "Bioethicists ask U of M Regents to appoint outside panel to review ethics of 2004 Dan Markingson case". MinnPost. Retrieved 2 December 2012.