| Portfolio | MEC |
|---|---|
| Premier | Panyaza Lesufi |
| e-Government | Bonginkosi Dhlamini |
| Finance and Economic Development | Lebogang Maile |
| Education and Sports, Arts, Culture and Recreation | Matome Chiloane |
| Health and Wellness | Nomantu Nkomo-Ralehoko |
| Roads and Transport | Kedibone Diale-Tlabela |
| Human Settlements | Tasneem Motara |
| Social Development | Faith Mazibuko |
| Agriculture and Rural Development | Vuyiswa Ramokgopa |
| Infrastructure Development and Cooperative Governance and Traditional Affairs | Jacob Mamabolo |
| Environment | Sheila Mary Peters |
