Talk:Protease

Description

Can someone add "protease segments protenes"? The description is a little klunky. There is no mention of how this word is pronounced. Is it "pro-teez" or "pro-tee-aze"? —Preceding unsigned comment added by 99.135.66.222 (talk) 16:18, 19 June 2010 (UTC)

"ase" means "breaker of." So it is protee-ase. Rumiton (talk) 14:08, 19 September 2010 (UTC)

Tool use

Can someone add some information what are proteases actually used for commercially? there are thousands of tons produced each year... Maximilianh

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—Preceding unsigned comment added by 157.136.241.109 (talk) 10:08, 6 November 2008 (UTC)

Protease is redirected here. Shouldn't it be the other way around? I used to do PhD studies on proteases... and the word "peptidase" exists in the name of a few proteases, but I think it is pretty oldfashioned. Protease was the word we used. / Habj 17:24, 11 August 2005 (UTC)

Endopeptidase? JFW | T@lk 18:42, 11 August 2005 (UTC)Where is it found?? in the pancreas and the stomach.

Not all proteases are endopeptidases. Endopeptidases are proteases that cleaves a protein chain in the middle of the sequence, while exoproteases "chews" from the end of the chain. /Habj 00:35, 15 August 2005 (UTC)

doesn't 'peptidases' refer primarily to the activity of proteases in the stomach? There is an inactive pro-peptidase that is turned into the active peptidase by acid (HCL) in the stomach. I think peptidases don't only inactivate proteins, like a protease does, but splits proteins without specificity into aminoacids --Picobyte 19:19, 21 March 2006 (UTC)

maybe this link is usefull? Extracellular proteases and their inhibitors ingenetic diseases of the central nervous system [1]

Possible image

Image:HIV protesase with ritonavir.png

User:TimVickers produced the following image which I nominated for deletion last week because it wasn't being used anywhere. User:Deryck Chan was nice enough to look through my nominations at my request and thought that this one was worth saving, and might be useful on this article. ~ BigrTex 16:55, 5 February 2007 (UTC)

Used this image elsewhere. —The preceding unsigned comment was added by Twooars (talk • contribs) 03:57, 15 April 2007 (UTC).

Peptidases

There could easily be a whole artical devoted to peptidases, rather than have it just redirected to this page. In a magazine I see an ad for a foot-care product has has protease as an ingredient; would "protease (subtilisin)" be effective for removing calluses? http://www.xenna.com/product_callex.html

Minor 2013 overhaul

I've made some changes that hopefully have improved the article:

• Finally cleared up orphan references from 2009!
  • I've integrated most into the text where it's obvious
  • The article is still a little sparse on references though
• Added leader image (though not necessarily the most appropriate)
• Added comparison of mechanisms and image (pretty proud of that one)
• Moved degradation section into mechanism and functions header
• Added evolutionary classification (MEROPS)
• Separated occurrence in to sections by kingdom
• Linked to main articles in inhibitors and uses
• Generally expanded a few sections
• Added see also links
• Do we need a history section?

Hopeully these justify increasing the article's quality class from Start to C. What do you think? T. Shafee (Evo&Evo) (talk) 02:54, 9 December 2013 (UTC)

fungi?

"Proteases can be found in animals, plants, bacteria, archea and viruses." Asmrulz (talk) 20:47, 1 May 2014 (UTC)

Assessment comment

The comment(s) below were originally left at Talk:Protease/Comments, and are posted here for posterity. Following several discussions in past years, these subpages are now deprecated. The comments may be irrelevant or outdated; if so, please feel free to remove this section.

This article is not accessible to a layman, and uses sentence forms which are confusing even for someone with the requisite background material. Instead of using run-on sentences with multiple commas and brackets, a better approach might even be using sentence fragments or point lists.

Last edited at 00:30, 11 June 2007 (UTC). Substituted at 03:28, 30 April 2016 (UTC)

Pronunciation

Could someone who knows how the IPA template works please add the pronunciation to the intro paragraph? Thanks. Psu256 (talk) 15:16, 18 September 2019 (UTC)

Circular defintion?

The Trypsin Wikipedia page starts "Trypsin (EC 3.4.21.4) is a serine protease..." and this Protease Wikipedia page begins "A protease (also called a peptidase or proteinase) is a Trypsin..."

I am not experienced enough in this field yet to know how to address this edit, but maybe one of you out there can help make this non-circular between the two pages! Cheers.