Talk:Germline mutation

Wiki Education Foundation-supported course assignment

This article is or was the subject of a Wiki Education Foundation-supported course assignment. Further details are available on the course page. Student editor(s): Cjp0001. Peer reviewers: Mrp0007, Jboyle0.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 21:46, 17 January 2022 (UTC)

Wiki Education Foundation-supported course assignment

This article is or was the subject of a Wiki Education Foundation-supported course assignment. Further details are available on the course page. Student editor(s): Kristinr.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 22:20, 16 January 2022 (UTC)

External links modified

Hello fellow Wikipedians,

I have just modified 2 external links on Germline mutation. Please take a moment to review my edit. If you have any questions, or need the bot to ignore the links, or the page altogether, please visit this simple FaQ for additional information. I made the following changes:

• Added archive https://web.archive.org/web/20111126004753/http://www.daisyfund.org/rb/about/genetics.html to http://www.daisyfund.org/rb/about/genetics.html
• Added archive https://web.archive.org/web/20100109185819/http://www.schizophreniaforum.org/for/curr/Malaspina/default.asp to http://www.schizophreniaforum.org/for/curr/Malaspina/default.asp

When you have finished reviewing my changes, you may follow the instructions on the template below to fix any issues with the URLs.

This message was posted before February 2018. After February 2018, "External links modified" talk page sections are no longer generated or monitored by InternetArchiveBot. No special action is required regarding these talk page notices, other than regular verification using the archive tool instructions below. Editors have permission to delete these "External links modified" talk page sections if they want to de-clutter talk pages, but see the RfC before doing mass systematic removals. This message is updated dynamically through the template {{source check}} (last update: 5 June 2024).

• If you have discovered URLs which were erroneously considered dead by the bot, you can report them with this tool.
• If you found an error with any archives or the URLs themselves, you can fix them with this tool.

Cheers.—InternetArchiveBot (Report bug) 03:24, 15 October 2017 (UTC)

Article Evaluation

The lead of this article provides an insightful understanding for the definition of a germline mutation, while also providing a brief description for each of the article's major components. Although vague in detail, the mention of it's occurrence, causes, clinical implications, and current therapies were present. This allows for viewers, like myself, to be informed of the exact content that is expected to follow. On a side note, this article can still be improved in some areas. There were a few sentences that could have been reworded for a better understanding. For example, the sentence, "This damage is rarely repaired imperfectly, but due to the high rate of germ cell division, can occur frequently." I had to go over this sentence numerous times to understand what was trying to be conveyed. It would have been easier to understand if it was written as, "Because of the high germ cell division rate, the damage occurs frequently, however, this damage is usually perfectly repaired." I would recommend adding more information about how common germline mutations occur and provide statistics to give viewers an idea of how many individuals are affected by such a mutation.

Another improvement that could be made involves creating two different sub-headings underneath the "Clinical Implications" heading. One for the role it plays in genetic diseases and another for the role it plays in different types of cancer. Not only would this help distinguish which category each of the conditions fall under, but it also allows for better organization of the article. In general, more information about how a germline mutation leads to different types of cancer would be a good improvement to this article. This section of the article did not contain enough detailed information and could be expanded upon. Nonetheless, this article possesses content that is up-to-date. While scrolling through the references, I noticed that a good portion of the cited sources were retrieved/published a few years ago. I found myself looking through these recent references that were cited, the latest one retrieved from 2018. Kaira Hosnedl (talk) 22:52, 6 September 2020 (UTC)