TAPSO is used to make buffer solutions. It has a pKa value of 7.635 (I=0, 25°C).[1] It can be used to make buffer solutions in the pH range 7.0-8.2.

TAPSO
Names
IUPAC name
3-[[1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl]amino]-2-hydroxypropane-1-sulfonic acid
Other names
3-[N-Tris(hydroxymethyl)methylamino]-2-hydroxypropanesulfonic acid
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.063.611 Edit this at Wikidata
UNII
  • InChI=1S/C7H17NO7S/c9-3-7(4-10,5-11)8-1-6(12)2-16(13,14)15/h6,8-12H,1-5H2,(H,13,14,15) ☒N
    Key: RZQXOGQSPBYUKH-UHFFFAOYSA-N ☒N
  • InChI=1/C7H17NO7S/c9-3-7(4-10,5-11)8-1-6(12)2-16(13,14)15/h6,8-12H,1-5H2,(H,13,14,15)
    Key: RZQXOGQSPBYUKH-UHFFFAOYAF
  • O=S(=O)(O)CC(O)CNC(CO)(CO)CO
Properties
C7H17NO7S
Molar mass 259.28 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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References

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  1. ^ Goldberg, R.; Kishore, N.; Lennen, R. (2002). "Thermodynamic Quantities for the Ionization Reactions of Buffers" (PDF). J. Phys. Chem. Ref. Data. 31 (2): 231–370. doi:10.1063/1.1416902. Archived from the original (PDF) on 2008-10-06. Retrieved 2017-07-13.