Suberedamines are chemical compounds that have been isolated from marine sponges in the genus Suberea.[1] The compounds are brominated tyrosine dimer derivatives.[2]

Suberedamine

Suberedamine A

Suberedamine B
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
  • A: InChI=1S/C23H30Br3N3O3/c1-29(2)9-4-10-32-22-18(25)12-16(13-19(22)26)7-8-28-23(30)20(27)14-15-5-6-21(31-3)17(24)11-15/h5-6,11-13,20H,4,7-10,14,27H2,1-3H3,(H,28,30)/t20-/m0/s1
    Key: CPOMDHYOIBOZBW-FQEVSTJZSA-N
  • B: InChI=1S/C24H32Br3N3O3/c1-28-21(15-16-6-7-22(32-4)18(25)12-16)24(31)29-9-8-17-13-19(26)23(20(27)14-17)33-11-5-10-30(2)3/h6-7,12-14,21,28H,5,8-11,15H2,1-4H3,(H,29,31)/t21-/m0/s1
    Key: MNNHZXNEKPRDII-NRFANRHFSA-N
  • A: CN(C)CCCOC1=C(C=C(C=C1Br)CCNC(=O)[C@H](CC2=CC(=C(C=C2)OC)Br)N)Br
  • B: CN[C@@H](CC1=CC(=C(C=C1)OC)Br)C(=O)NCCC2=CC(=C(C(=C2)Br)OCCCN(C)C)Br
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

References

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  1. ^ Kottakota, S. K.; Evangelopoulos, D.; Alnimr, A.; Bhakta, S.; McHugh, T. D.; Gray, M.; Groundwater, P. W.; Marrs, E. C.; Perry, J. D.; Spilling, C. D.; Harburn, J. J. (2012). "Synthesis and biological evaluation of purpurealidin E-derived marine sponge metabolites: aplysamine-2, aplyzanzine A, and suberedamines A and B". Journal of Natural Products. 75 (6): 1090–101. doi:10.1021/np300102z. PMID 22620987.
  2. ^ Zhou, Jiaju (23 September 2019). Alkaloids, Part 1. Walter de Gruyter GmbH & Co KG. pp. 112–113. ISBN 978-3-11-065519-3.

Extra reading

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