Glenna Shirleen Roeder is a geneticist known for identifying and characterizing the yeast genes that regulate the process of meiosis with particular emphasis on synapsis.
G. Shirleen Roeder | |
|---|---|
| Alma mater | University of Toronto |
| Scientific career | |
| Thesis | Recombination, maturation and packaging of the bacteriophage T7 chromosome (1978) |
Education and career
editRoeder has a B.Sc. from Dalhousie University (1973)[1][2] and earned her Ph.D. in 1978 from the University of Toronto.[3] Following her Ph.D. she was a postdoctoral fellow at Cornell University before moving to the faculty at Yale University in 1981.[4] In 2001 she was named the Eugene Higgins Professor of Genetics in the Molecular, Cellular, and Developmental Biology Department at Yale University.[4] Roeder retired in 2012[1] and, as of 2021, she is Professor Emeritus at Yale University.[5]
Research
editRoeder used budding yeast as a model system to examine meiosis. She discovered the Zip1 protein,[6] and discovered two distinct processes that regulate the recombination between chromosomes in meiosis and also a process inhibiting recombination.[7]
Selected publications
edit- Roeder, G. Shirleen (15 October 1997). "Meiotic chromosomes: it takes two to tango". Genes & Development. 11 (20): 2600–2621. doi:10.1101/gad.11.20.2600. ISSN 0890-9369. PMID 9334324.
- Sym, Mary; Engebrecht, JoAnne; Roeder, G. Shirleen (12 February 1993). "ZIP1 is a synaptonemal complex protein required for meiotic chromosome synapsis". Cell. 72 (3): 365–378. doi:10.1016/0092-8674(93)90114-6. ISSN 0092-8674. PMID 7916652. S2CID 6174855.
- Roeder, G. Shirleen; Bailis, Julie M. (1 September 2000). "The pachytene checkpoint". Trends in Genetics. 16 (9): 395–403. doi:10.1016/S0168-9525(00)02080-1. ISSN 0168-9525. PMID 10973068.
- Ross-Macdonald, Petra; Roeder, G. Shirleen (16 December 1994). "Mutation of a meiosis-specific MutS homolog decreases crossing over but not mismatch correction". Cell. 79 (6): 1069–1080. doi:10.1016/0092-8674(94)90037-X. ISSN 0092-8674. PMID 8001134. S2CID 28539509.
Awards and honors
editIn 1984, Roeder received a Young Investigator award from the National Science Foundation.[8] She was named an HHMI investigator in 1997,[9] and was elected to the National Academy of Sciences in 2009.[7] In 2010, she was chosen as a Fellow of the American Association for the Advancement of Science[10] and elected to the American Academy of Microbiology.[11][12]
References
edit- ^ a b "Faculty retirement tribute to G. Shirleen Roeder". Yale University. 2012. Archived from the original on December 30, 2021. Retrieved December 30, 2021.
- ^ "science.ca : Shirleen Roeder". www.science.ca. Retrieved 2021-12-30.
- ^ Roeder, Glenna Shirleen (1978). Recombination, maturation and packaging of the bacteriophage T7 chromosome (Thesis). Toronto: [publisher not identified].
- ^ a b "Geneticist Shirleen Roeder named Eugene Higgins Professor". Yale Bulletin and Calendar. June 15, 2001. Retrieved 2021-12-30.
- ^ "G Shirleen Roeder, Ph.D. | Molecular, Cellular and Developmental Biology". mcdb.yale.edu. Retrieved 2021-12-30.
- ^ Sym, Mary; Engebrecht, JoAnne; Roeder, G. Shirleen (12 February 1993). "ZIP1 is a synaptonemal complex protein required for meiotic chromosome synapsis". Cell. 72 (3): 365–378. doi:10.1016/0092-8674(93)90114-6. ISSN 0092-8674. PMID 7916652. S2CID 6174855.
- ^ a b ""G Shirleen Roeder, Yale University"". National Academy of Sciences. Retrieved November 14, 2018.
- ^ "NSF Award Search: Award # 8351607 - Presidential Young Investigator Award". www.nsf.gov. Retrieved 2021-12-30.
- ^ ""G. Shirleen Roeder, PhD"". Howard Hughes Medical Institute. Retrieved November 14, 2018.
- ^ Luna, Regina (September 1, 2010). ""Yale Scientists Awarded AAAS Fellowship"". Yale Scientific. Retrieved November 14, 2018.
- ^ ""AAM Fellows G. Shirleen Roeder"". American Academy of Microbiology. Retrieved November 14, 2018.
- ^ "78 scientists elected to the American Academy of Microbiology". EurekAlert!. Retrieved 2021-12-30.
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