SDF4

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45 kDa calcium-binding protein is a protein that in humans is encoded by the SDF4 gene.

SDF4
Identifiers
Aliases	SDF4, Cab45, SDF-4, stromal cell derived factor 4
External IDs	OMIM: 614282; MGI: 108079; HomoloGene: 32121; GeneCards: SDF4; OMA:SDF4 - orthologs
Gene location (Human) Chr. Chromosome 1 (human) Band 1p36.33 Start 1,216,909 bp End 1,232,067 bp
Gene location (Mouse) Chr. Chromosome 4 (mouse) Band 4|4 E2 Start 156,077,329 bp End 156,098,067 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in stromal cell of endometrium right hemisphere of cerebellum cartilage tissue mucosa of transverse colon thoracic aorta ascending aorta Descending thoracic aorta right auricle cardia right coronary artery Top expressed in stroma of bone marrow molar supraoptic nucleus dentate gyrus of hippocampal formation granule cell spermatocyte mesenteric lymph nodes calvaria right lung lobe duodenum superior frontal gyrus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding metal ion binding identical protein binding calcium ion binding Cellular component cell projection extracellular exosome bleb late endosome Golgi lumen cytoplasm membrane plasma membrane Golgi apparatus endoplasmic reticulum Biological process UV protection zymogen granule exocytosis response to ethanol cerebellum development calcium-ion regulated exocytosis exocytosis fat cell differentiation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 51150 20318 Ensembl ENSG00000078808 ENSMUSG00000029076 UniProt Q9BRK5 Q61112 RefSeq (mRNA) NM_016176 NM_016547 NM_011341 NM_001302467 NM_001302468 NM_001302469 RefSeq (protein) NP_057260 NP_057631 NP_001289396 NP_001289397 NP_001289398 NP_035471 Location (UCSC) Chr 1: 1.22 – 1.23 Mb Chr 4: 156.08 – 156.1 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Further reading

• Honoré B, Vorum H (2000). "The CREC family, a novel family of multiple EF-hand, low-affinity Ca(2+)-binding proteins localised to the secretory pathway of mammalian cells". FEBS Lett. 466 (1): 11–8. doi:10.1016/S0014-5793(99)01780-9. PMID 10648803.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.
• Lam PP, Hyvärinen K, Kauppi M, et al. (2007). "A cytosolic splice variant of Cab45 interacts with Munc18b and impacts on amylase secretion by pancreatic acini". Mol. Biol. Cell. 18 (7): 2473–80. doi:10.1091/mbc.E06-10-0950. PMC 1924827. PMID 17442889.