Raul Andino is a virologist and professor in the Department of Microbiology and Immunology at the University of California, San Francisco.[2] He is noted for leading a team of researchers that developed the first new oral polio vaccine in 50 years.[3]
Raul Andino | |
|---|---|
| Born | 1957 |
| Awards | Beijerinck Virology Prize (2017)[1] |
| Academic background | |
| Academic advisors | David Baltimore |
| Academic work | |
| Doctoral students | Shane Crotty (2001) |
Early life and education
editRaul Andino was born in 1957[1] in Argentina.[4] He completed his master's degree in Biology in 1980 and his Ph.D. in Chemistry in 1986, both at the University of Buenos Aires.[2]
Andino emigrated to the United States in the 1980s.[4] He then went on to work as a postdoctoral researcher first at the Whitehead Institute for Biomedical Research from 1986 to 1991, then at Rockefeller University in the lab of David Baltimore from 1991 to 1992.[2] He then joined the faculty of the University of California, San Francisco as an assistant professor.[2] He was promoted to associate professor in 1999, then full professor in 2003.[2]
Research
editRaul Andino's research has long focused on poliovirus. Together with Andrew Macadam, Andino redesigned the polio vaccine so it can stop the virus from re-evolving.[5][6] His research has expanded to other enteroviruses and host defenses against other RNA viruses.[1] His group has also had a long-standing interest in RNA interference as an antiviral defense, and in the dynamics of viral evolution during infection and transmission.[1]
Notable publications
edit- Vignuzzi M, Stone JK... Andino R (2006). Quasispecies diversity determines pathogenesis through cooperative interactions in a viral population. Nature. 439(7074): pgs. 344-348
- Gitlin L, Karelsky S, Andino R (2002). Short interfering RNA confers intracellular antiviral immunity in human cells. Nature. 418(6896): pgs. 430-434
- Crotty S, Camerson SE, Andino R (2001). RNA virus error catastrophe: direct molecular test using ribavirin. Proceedings of the National Academy of Sciences of the United States of America. 98(12): pgs. 6895-6900
- Gamarnik AV, Andino R (1998). Switch from translation to RNA replication in a positive-stranded RNA virus. Genes and Development. 12(15) pgs. 2293-2304
- Andino R, Rieckhof GE... Baltimore D (1993). Poliovirus RNA synthesis utilizes an RNP complex formed around the 5'-end of the viral RNA. EMBO Journal. 12(9): pgs. 3587-3598
References
edit- ^ a b c d "Academy Beijerinck Prize for American Virologyo Raul Andino". Koninkllejke Nederlandse Akademie van Wetenschappen. 27 February 2017. Retrieved 11 July 2019.
- ^ a b c d e "Raul Andino, PhD". UCSF. Retrieved 11 July 2019.
- ^ "'Designer Virus' is First New Polio Vaccine in 50 Years". ‘Designer Virus’ is First New Polio Vaccine in 50 Years | UC San Francisco. 23 April 2020. Retrieved 2020-06-23.
- ^ a b Christian, Carlos (2020-06-12). "The first polio vaccine in half a century reactivates the hope of eradicating a disease again | Future Planet | The Union Journal". Retrieved 2020-06-23.
- ^ Rees, Victoria (April 28, 2020). "Researchers design first new polio vaccine in 50 years". EPR. Retrieved June 24, 2010.
- ^ Kaltwasser, Jared (May 4, 2020). "New Oral Polio Vaccine Candidate Could Signal Strategy to Fight COVID-19". ContagionLive. Retrieved 2020-06-23.