Ralf Jungmann is a German physicist and Full Professor (Physics) and Chair for Molecular Physics of Life at the Ludwig Maximilian University of Munich, Germany. He is known for his contributions to the development of super-resolution microscopy techniques. In particular, he is known for his work on DNA-PAINT, a super-resolution technique that uses short DNA strands to label and locate specific molecules within a sample with high precision.
Ralf Jungmann | |
|---|---|
| Nationality | German |
| Alma mater | |
| Known for | DNA-PAINT |
| Scientific career | |
| Fields | Super-Resolution Microscopy, DNA Nanotechnology, Biophysics, Single Molecule Experiments |
| Institutions | |
| Thesis | DNA origami as a molecular platform for bionanotechnology (2010) |
| Doctoral advisor | Friedrich Simmel |
| Website | Jungmann Lab |
Education
editBetween 2001 and 2006, Jungmann pursued a degree in Physics at Saarland University and the University of California, Santa Barbara. During his time at the latter institution, he conducted his Diploma thesis under the guidance of Paul K. Hansma. Subsequently, from 2007 to 2010, he completed his Ph.D. in Physics at Technical University of Munich, where he worked in the laboratory of Friedrich Simmel.
Career and research
editBetween 2011 and 2014, Jungmann served as a postdoctoral researcher at the Wyss Institute for Biologically Inspired Engineering at Harvard University, working under the guidance of Peng Yin and William M Shih.
In 2014, Jungmann returned to the Germany to work as a Research group Leader at the Max Planck Institute of Biochemistry and the Ludwig Maximilian University of Munich.
Jungmann's professional career advanced significantly, with him being promoted to different positions throughout the years. He was appointed as an Associate Professor (Physics) Tenure Track in 2016, followed by his promotion to Associate Professor (Physics) with Tenure in 2021. In 2023, he was appointed as Full Professor (Physics) and Chair for Molecular Physics of Life.
Jungmann's research primarily focuses on developing and applying new biophysical and imaging techniques, especially super-resolution microscopy, to investigate the organization and function of biological systems at the molecular level. His work has important applications in the study of various biological processes, including gene expression, protein interactions, and cellular signaling, and has contributed to the development of nanotechnology and DNA-based computing.
Jungmann is particularly well known for his contributions to the development of DNA-PAINT,[1][2][3][4] a super-resolution technique that uses short DNA strands to accurately label and locate specific molecules within a sample, leading to new insights into the structure and function of cells.
Awards and honours
editReferences
edit- ^ Jungmann, Ralf; Avendaño, Maier S.; Woehrstein, Johannes B.; Dai, Mingjie; Shih, William M.; Yin, Peng (2014). "Multiplexed 3D cellular super-resolution imaging with DNA-PAINT and Exchange-PAINT". Nature Methods. 11 (3): 313–318. doi:10.1038/nmeth.2835. PMC 4153392. PMID 24487583.
- ^ Jungmann, Ralf; Avendaño, Maier S.; Dai, Mingjie; Woehrstein, Johannes B.; Agasti, Sarit S.; Feiger, Zachary; Rodal, Avital; Yin, Peng (2016). "Quantitative super-resolution imaging with qPAINT". Nature Methods. 13 (5): 439–442. doi:10.1038/nmeth.3804. PMC 4941813. PMID 27018580.
- ^ Schnitzbauer, Joerg; Strauss, Maximilian T.; Schlichthaerle, Thomas; Schueder, Florian; Jungmann, Ralf (2017). "Super-resolution microscopy with DNA-PAINT". Nature Protocols. 12 (6): 1198–1228. doi:10.1038/nprot.2017.024. PMID 28518172.
- ^ Lelek, Mickaël; Gyparaki, Melina T.; Beliu, Gerti; Schueder, Florian; Griffié, Juliette; Manley, Suliana; Jungmann, Ralf; Sauer, Markus; Lakadamyali, Melike; Zimmer, Christophe (2021). "Single-molecule localization microscopy". Nature Reviews Methods Primers. 1. doi:10.1038/s43586-021-00038-x. PMC 9160414. PMID 35663461.
- ^ https://erc.europa.eu/sites/default/files/document/file/erc_2015_stg_results_ls.pdf
- ^ "From Tissues to Single Molecules: High Content in Situ Super-Resolution imaging with DNA-PAINT | MolMap Project | Fact Sheet | H2020".
- ^ "ERC Consolidator Grant to Ralf Jungmann - SFB 1032: Nanoagents for Spatiotemporal Control of Molecular and Cellular Reactions - LMU Munich".
- ^ "Imaging Receptomics as a tool for biomedical discovery | ReceptorPAINT Project | Fact Sheet | H2020".