Río de Oro is one of the two territories that formed the Spanish province of Spanish Sahara after 1969.
Río de Oro may also refer to:
- Río de Oro, Cesar, a town in Colombia
- Río de Oro (Melilla), a river in Morocco
- Río de Oro (Argentina), a river in Argentina
- Río de Oro (Catatumbo), a river in Colombia and Venezuela