Pragma, an abbreviation for pragmatic, or from the same root, may refer to:
- πράγμα, the Ancient Greek word; see pragmatism
- Directive (programming), also known as a pragma or pragmat in several programming languages
- Pragma (love), a model of love
- Pragma (periodical), a 1980's publication for Pick operating system users
- Pragma (album), a 1998 album by Tim Hodgkinson