Polyglycylation is a form of posttranslational modification of glutamate residues of the carboxyl-terminal region tubulin in certain microtubules (e.g., axonemal) originally discovered in Paramecium,[1] and later shown in mammalian neurons as well.[2]

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References

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  1. ^ Redeker V, Levilliers N, Schmitter JM, Le Caer JP, Rossier J, Adoutte A, Bré MH (1994). "Polyglycylation of tubulin: a posttranslational modification in axonemal microtubules". Science. 266 (5191): 1688–1691. Bibcode:1994Sci...266.1688R. doi:10.1126/science.7992051. PMID 7992051.
  2. ^ Banerjee Asok (2002). "Coordination of posttranslational modifications of bovine brain alpha-tubulin. Polyglycylation of delta2 tubulin". J. Biol. Chem. 277 (48): 46140–46144. doi:10.1074/jbc.M208065200. PMID 12356754.