Pinocembrin is a flavanone, a type of flavonoid. It is an antioxidant found in damiana,[1] honey, fingerroot,[2] and propolis.[3]

Pinocembrin
Names
IUPAC name
5,7-Dihydroxy-2-phenyl-2,3-dihydro-4H-chromen-4-one
Other names
Dihydrochrysin
Galangin flavanone
5,7-Dihydroxyflavanone
5,7-Dihydroxy-2-phenyl-2,3-dihydro-4H-chromen-4-one
4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-phenyl-
5,7-Dihydroxy-2-phenyl-chroman-4-one
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
KEGG
UNII
  • InChI=1S/C15H12O4/c16-10-6-11(17)15-12(18)8-13(19-14(15)7-10)9-4-2-1-3-5-9/h1-7,13,16-17H,8H2 checkY
    Key: URFCJEUYXNAHFI-UHFFFAOYSA-N checkY
  • InChI=1/C15H12O4/c16-10-6-11(17)15-12(18)8-13(19-14(15)7-10)9-4-2-1-3-5-9/h1-7,13,16-17H,8H2
    Key: URFCJEUYXNAHFI-UHFFFAOYAA
  • O=C2c3c(OC(c1ccccc1)C2)cc(O)cc3O
Properties
C15H12O4
Molar mass 256.257 g·mol−1
Density 1.386 g/mL
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Pinocembrin can be converted biosynthetically to pinobanksin by hydroxylation.

See also

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References

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  1. ^ Zhao, J; Dasmahapatra AK; Khan SI; Khan IA (Dec 2008). "Anti-aromatase activity of the constituents from damiana (Turnera diffusa)". J Ethnopharmacol. 120 (3): 387–393. doi:10.1016/j.jep.2008.09.016. PMID 18948180.
  2. ^ Punvittayagul, C; Wongpoomchai R; Taya S; Pompimon W. (January 2011). "Effect of pinocembrin isolated from Boesenbergia pandurata on xenobiotic-metabolizing enzymes in rat liver". Drug Metabolism Letters. 5 (1): 1–5. doi:10.2174/187231211794455226. PMID 20942797.
  3. ^ Bosio K; Avanzini C; D’Avolio A; Ozino O; Savoia D (2000). "In vitro activity of propolis against Streptococcus pyogenes". Letters in Applied Microbiology. 31 (2): 174–177. doi:10.1046/j.1365-2672.2000.00785.x. PMID 10972723. S2CID 1622868.
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